Profile

Name

Mizuho Kajikawa

Affiliation

Laboratory of Integrative Infection Immunology

Subjects

Foundation in Microbiology
Emergency＆Re-emergency Infectious Diseases

Official title

Lecturer

Degree

Ph. D.

Research fields

Microbiology

Structural Biology

Papers

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• [Original paper]　The NADPH oxidase NOX4 promotes the directed migration of endothelial cells by stabilizing vascular endothelial growth factor receptor 2 protein.　Miyano K, Okamoto S, Yamauchi A, Kawai C, Kajikawa M, Kiyohara T, Tamura M, Taura M, Kuribayashi F.　J Biol Chem.　295(33)　11877–11890　2020　
• [Original paper]　The Mitochondrial Inner Membrane Protein LETM1 Modulates Cristae Organization Through Its LETM Domain.　Nakamura S, Matsui A, Akabane S, Tamura Y, Hatano A, Miyano Y, Omote H, Kajikawa M, Maenaka K, Moriyama Y, Endo T, Oka T.　Commun Biol.　3(1)　99　2020　
• [Review]　MHC Class II Fine Tuning by Ubiquitination: Lesson From MARCHs.　Ishido S, Kajikawa M.　Immunogenetics　71(3)　197-201　2019　
• [Original paper]　Specificity of Morbillivirus Hemagglutinins to Recognize SLAM of Different Species.　Fukuhara H, Ito Y, Sako M, Kajikawa M, Yoshida K, Seki F, Mwaba MH, Hashiguchi T, Higashibata MA, Ose T, Kuroki K, Takeda M, Maenaka K.　Viruses　11(8)　E761　2019　
• [Original paper]　Structure of MHC Class I-like MILL2 Reveals Heparan-Sulfate Binding and Interdomain Flexibility.　Kajikawa M, Ose T, Fukunaga Y, Okabe Y, Matsumoto N, Yonezawa K, Shimizu N, Kollnberger S, Kasahara M, Maenaka K.　Nat Commun.　9(1)　4330　2018　
• [Original paper]　NKG2D triggers cytotoxicity in murine epidermal γδ T cells via PI3K-dependent, Syk/ZAP70-independent signaling pathway.　Ibusuki A, Kawai K, Yoshida S, Uchida Y, Nitahara-Takeuchi A, Kuroki K, Kajikawa M, Ose T, Maenaka K, Kasahara M, Kanekura T.　J Invest Dermatol.　134(2)　396-404　2014　
• [Original paper]　Loss of MHC II ubiquitination inhibits the activation and differentiation of CD4 T cells.　Ishikawa R, Kajikawa M, Ishido S.　Int Immunol.　26(5)　283-289　2014　
• [Original paper]　Structural basis for simultaneous recognition of an O-glycan and its attached peptide of mucin family by immune receptor PILRα.　Kuroki K, Wang J, Ose T, Yamaguchi M, Tabata S, Maita N, Nakamura S, Kajikawa M, Kogure A, Satoh T, Arase H, Maenaka K.　Proc Natl Acad Sci U S A.　111(24)　8877-8882　2014　
• [Original paper]　The long-term immunosuppressive effects of disulfide-linked HLA-G dimer in mice with collagen-induced arthritis.　Kuroki K, Hirose K, Okabe Y, Fukunaga Y, Takahashi A, Shiroishi M, Kajikawa M, Tabata S, Nakamura S, Takai T, Koyanagi S, Ohdo S, Maenaka K.　Hum Immunol.　74(4)　433-438　2013　
• [Original paper]　The intertransmembrane region of Kaposi's sarcoma-associated herpesvirus modulator of immune recognition 2 contributes to B7-2 downregulation.　Kajikawa M, Li PC, Goto E, Miyashita N, Aoki-Kawasumi M, Mito-Yoshida M, Ikegaya M, Sugita Y, Ishido S.　J Virol.　86(9)　5288-5296　2012　
• [Original paper]　Involvement of an NKG2D ligand H60c in epidermal dendritic T cell-mediated wound repair.　Yoshida S, Mohamed RH, Kajikawa M, Koizumi J, Tanaka M, Fugo K, Otsuka N, Maenaka K, Yagita H, Chiba H, Kasahara M.　J Immunol.　188(8)　3972-3979　2012　
• [Original paper]　Molecular basis for herpesvirus entry mediator recognition by the human immune inhibitory receptor CD160 and its relationship to the cosignaling molecules BTLA and LIGHT.　Kojima R, Kajikawa M, Shiroishi M, Kuroki K, Maenaka K.　J Mol Biol.　413(4)　762-772　2011　
• [Review]　Silkworm expression system as a platform technology in life science.　Kato T, Kajikawa M, Maenaka K, Park EY.　Appl Microbiol Biotechnol.　85(3)　459-470　2010　
• [Review]　MARCH-I: a new regulator of dendritic cell function.　Ishido S, Matsuki Y, Goto E, Kajikawa M, Ohmura-Hoshino M.　Mol Cells.　29(3)　229-232　2010　
• [Original paper]　Contribution of lysine 11-linked ubiquitination to MIR2-mediated major histocompatibility complex class I internalization.　Goto E, Yamanaka Y, Ishikawa A, Aoki-Kawasumi M, Mito-Yoshida M, Ohmura-Hoshino M, Matsuki Y, Kajikawa M, Hirano H, Ishido S.　J Biol Chem.　285(46)　35311-35319　2010　
• [Original paper]　Efficient silkworm expression of human GPCR (nociceptin receptor) by a Bombyx mori bacmid DNA system.　Kajikawa M, Sasaki K, Wakimoto Y, Toyooka M, Motohashi T, Shimojima T, Takeda S, Park EY, Maenaka K.　Biochem Biophys Res Commun.　385(3)　375-379　2009　
• [Original paper]　Silkworm expression and sugar profiling of human immune cell surface receptor, KIR2DL1.　Sasaki K, Kajikawa M, Kuroki K, Motohashi TSasaki K, Kajikawa M, Kuroki K, Motohashi T, Shimojima T, Park EY, Kondo S, Yagi H, Kato K, Maenaka K., Shimojima T, Park EY, Kondo S, Yagi H, Kato K, Maenaka K.　Biochem Biophys Res Commun.　387(3)　575-580　2009　
• [Original paper]　Molecular basis for E-cadherin recognition by killer cell lectin-like receptor G1 (KLRG1).　Nakamura S, Kuroki K, Ohki I, Sasaki K, Kajikawa M, Maruyama T, Ito M, Kameda Y, Ikura M, Yamamoto K, Matsumoto N, Maenaka K.　J Biol Chem.　284(40)　27327-27335　2009　
• [Original paper]　Two novel NKG2D ligands of the mouse H60 family with differential expression patterns and binding affinities to NKG2D.　Takada A, Yoshida S, Kajikawa M, Miyatake Y, Tomaru U, Sakai M, Chiba H, Maenaka K, Kohda D, Fugo K, Kasahara M.　J Immunol.　180(3)　1678-1685　2008　
• [Original paper]　Biophysical characterization of O-glycosylated CD99 recognition by paired Ig-like type 2 receptors.　Tabata S, Kuroki K, Wang J, Kajikawa M, Shiratori I, Kohda D, Arase H, Maenaka K.　J Biol Chem.　283(14)　8893-8901　2008　
• [Original paper]　Homogeneous sugar modification improves crystallization of measles virus hemagglutinin.　Hashiguchi T, Kajikawa M, Maita N, Takeda M, Kuroki K, Sasaki K, Kohda D, Yanagi Y, Maenaka K.　J Virol Methods.　149(1)　171-174　2008　
• [Original paper]　Detection of weak ligand interactions of leukocyte Ig-like receptor B1 by fluorescence correlation spectroscopy.　Kuroki K, Kobayashi S, Shiroishi M, Kajikawa M, Okamoto N, Kohda D, Maenaka K.　J Immunol Methods.　320(1-2)　172-176　2007　
• [Original paper]　Crystal structure of measles virus hemagglutinin provides insight into effective vaccines.　Hashiguchi T, Kajikawa M, Maita N, Takeda M, Kuroki K, Sasaki K, Kohda D, Yanagi Y, Maenaka K.　Proc Natl Acad Sci U S A.　104(49)　19535-19540　2007　
• [Original paper]　Crystal structure of the human monocyte-activating receptor, "Group 2" leukocyte Ig-like receptor A5 (LILRA5/LIR9/ILT11).　Shiroishi M, Kajikawa M, Kuroki K, Ose T, Kohda D, Maenaka K.　J Biol Chem.　281(28)　19536-19544　2006　
• [Original paper]　MHC class I-like MILL molecules are beta2-microglobulin-associated, GPI-anchored glycoproteins that do not require TAP for cell surface expression.　Kajikawa M, Baba T, Tomaru U, Watanabe Y, Koganei S, Tsuji-Kawahara S, Matsumoto N, Yamamoto K, Miyazawa M, Maenaka K, Ishizu A, Kasahara M.　J Immunol.　177(5)　3108-3115　2006　

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Conference, etc.

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• [Poster presentation]　Substrate recognition by viral membrane-associated E3 ubiquitin ligases　Mizuho Kajikawa　The 35th Naito Conference　Sapporo　2012/07/09〜07/12
• [Poster presentation]　Molecular basis for immunoreceptor recognition by MIR2 ubiquitin ligase of KSHV　Mizuho Kajikawa, Eiji Goto, Pai-Chi Li, Naoyuki Miyashita, Masami Aoki-Kawasumi, Mari Mito, Yuji Sugita, Satoshi Ishido　IUMS2011：International Union of Microbiological Societies 2011　Sapporo　2011/09/11〜09/16

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