Profile

Name

Etsu Tashiro

Affiliation

Laboratory of Biochemistry

Subjects

Biochemistry I
Biochemistry II

Official title

Associate Professor

Degree

Ph.D.

Books

Download TSV file

• Bioprobe 2^nd edition “Biochemical Tools for Investigating Cell Function”　Tashiro E, Kitagawa M and Imoto M　Chapter 4　75-114　Springer　2017　
• Control of Cellular Physiology by E2F Transcription Factors　Minato Y, Tashiro E, Kanai M and Imoto M　　153-165　　2008　

• View all

Papers

Download TSV file

• [Original paper]　Ktedonoketone and 2'-oxosattabacin, benzenoid metabolites from a thermophilic bacterium Thermosporothrix hazakensis in the phylum Chloroflexi　Igarashi Y, Yamamoto K, Ueno C, Yamada N, Saito K, Takahashi K, Enomoto M, Kuwahara S, Oikawa T, Tashiro E, Imoto M, Xiaohnyao Y, Zhou T, Harunari E, Oku N.　J Antibiot (Tokoyo)　72　653　2019　
• [Review]　Screening and identification of inhibitors of endoplasmic reticulum stress-induced activation of the IRE1α-XBP1 branch　Tashiro E　J Antibiot (Tokoyo)　72　899　2019　
• [Original paper]　14-3-3εa directs the pulsatile transport of basal factors towards the apical domain for lumen growth in tubulogenesis　Mizotani Y, Suzuki M, Hotta K, Watanabe H, Shiba K, Inaba K, Tashiro E, Oka K, Imoto M.　PNAS　115　E8873　2018　
• [Original paper]　Metacycloprodigiosin induced cell death selectively in β-catenin-mutated tumor cells　Ikeda H, Shikata Y, Watanapokasin R, Tashiro E, Imoto M　J Antibiot (Tokoyo)　70　109　2017　
• [Original paper]　Protein kinase A inhibition facilitates the antitumor activity of xanthohumol, a valosin-containing protein inhibitor　Shikata Y, Yoshimaru T, Komatsu M, Katoh H, Sato R, Kanagaki S, Okazaki Y, Toyokuni S, Tashiro E, Ishikawa S, Katagiri T, Imoto M　Cancer Sci　108　785　2017　
• [Original paper]　Nonthmicin, a Polyether Polyketide Bearing a Halogen-Modified Tetronate with Neuroprotective and Antiinvasive Activity from Actinomadura sp.　Igarashi Y, Natsuoka N, In Y, Kataura T, Tashiro E, Saiki I, Sudoh Y, Duangmal K, Thamchaipenet A　Org Lett　19　1406　2017　
• [Review]　Chemistry and biology of the compounds that modulate cell migration　Tashiro E and Imoto M　J Ind Microbiol Biotechnol　43　213　2016　
• [Original paper]　Involvement of the MEK/ERK pathway in EGF-induced E-cadherin down-regulation　Tashiro E, Henmi S, Odake H, Ino S, Imoto M　Biochem Biophys Res Commun　477　801　2016　
• [Original paper]　SMK-17, a MEK1/2-specific inhibitor, selectively induces apoptosis in β-catenin-mutated tumors　Kiga M, Nakayama A, Shikata Y, Sasazawa Y, Murakami R, Nakanishi T, Tashiro E, and Imoto M　Sci Rep　5　8155　2015　
• [Original paper]　Apoptosis induction associated with the ER stress response through up-regulation of JNK in HeLa cells by gambogic acid　Krajamg A, Imoto M, Tashiro E, Fujimaki T, Shinjo S, and Watanapokasin R　BMC Complement Altem Med　15　26　2015　
• [Original paper]　Evaluation of drug toxicity profiles based on the phenotypes of ascidian Ciona intestinalis　Mizotani Y, Itoh S, Hotta K, Tashiro E, Oka K, and Imoto M　Biochem Biophys Res Commun　463　656　2015　
• [Review]　Chemical biology of compounds obtained from screening using disease models　Tashiro E and Imoto M　Arch Pharm Res　38　1651　2015　
• [Original paper]　5-lipoxygenase and cysteinyl leukotriene receptor 1 regulate epidermal growth factor-induced cell migration through Tiam1 upregulation and Rac1 activation　Magi S, Takemoto Y, Kobayashi H, Kasamatsu M, Akita T, Tanaka A, Takano K, Tashiro E, Igarashi Y, and Imoto M　Cancer Sci　105　290　2014　
• [Original paper]　Chemical genomic-based pathway analyses for epidermal growth factor-mediated signaling in migrating cancer cells　Magi S, Saeki Y, Kasamatsu M, Tashiro E, and Imoto M　PLoS One　9　e96776　2014　
• [Original paper]　Identification of licopyranocoumarin and glycyrurol from herbal medicines as neuroprotective compounds for Parkinson’s disease　Fujimaki T, Saiki S, Tashiro E, Yamada D, Kitagawa M, Hattori N, and Imoto M　PLoS One　9　e100395　2014　
• [Original paper]　Xanthohumol suppresses oestrogen-signaling in breast cancer through the inhibition of BIG3-PHB2 interactions　Yoshimaru T, Komatsu M, Tashiro E, Imoto M, Osada H, Miyoshi Y, Honda J, Sasa M, and Katagiri T　Sci Rep　4　7355　2014　
• [Original paper]　Boronic Acid Inhibitors of Acyl Protein Thioesterase 1 and 2　Zimmermann TJ, Burger M, Tashiro E, Kondoh Y, Martinez NE, Gormer K, Rosin-Steiner S, Shimizu T, Ozaki S, Mikoshiba K, Watanabe N, Hall D, Vetter IR, Osada H, Hedberg C and Waldmann H　Chembiochem　14　115　2013　
• [Original paper]　Novel derivatives of aclacinomycin A block cancer cell migration through inhibition of farnesyl transferase　Magi S, Shitara T, Takemoto Y, Sawada M, Kitagawa M, Tashiro E, Takahashi Y and Imoto M　J Antibiot (Tokoyo)　66　165　2013　
• [Original paper]　Comparative Analysis of the UPR-Target Genes Expression Patterns induced by UPR-Inducing Compounds　Shinjo S, Mizotani Y, Tashiro E and Imoto M　Biosci Biotechnol Biochem　77　729　2013　
• [Original paper]　Establishment of a new detection system for the dimerization of IRE1α using a BiFC assay　Shinjo S, Tashiro E and Imoto M　Biosci Biotechnol Biochem　77　1333　2013　
• [Original paper]　Antitumor effects of novel highly hydrophilic and non-ATP-competitive MEK1/2 inhibitor, SMK-17　Kiga M, Tanzawa F, Iwasaki S, Inaba F, Fujiwara K, Iwadare H, Echigo T, Nakamura Y, Shibata T, Suzuki K, Yasumatsu I, Nakayama A, Sasazawa Y, Tashiro E, Imoto M and Kurakata S　Anticancer Drugs　23　119　2012　
• [Review]　Target identification of bioactive compounds　Tashiro E and Imoto M　Bioorg Med Chem　20　1910　2012　
• [Original paper]　Napyradiomycin A1, an inhibitor of mitochondrial complex I and II　Yamamoto K, Tashiro E, Motohashi K, Seto H and Imoto M　J Antibiot (Tokoyo)　65　211　2012　
• [Original paper]　Xanthohumol impairs autophagosome maturation through direct inhibition of valosin-containing protein　Sasazawa Y, Kanagaki S, Tashiro E, Nogawa T, Muroi M, Kondoh Y, Osada H and Imoto M　ACS Chem Biol　7　892　2012　
• [Original paper]　Inostamycin enhanced TRAIL-induced apoptosis through DR5 up-regulation on the cell surface　Yamamoto K, Makino M, Watanapokasin R, Tashiro E and Imoto M　J Antibiot (Tokoyo)　65　295　2012　
• [Original paper]　Identification of Toyocamycin, an agent cytotoxic for multiple myeloma cells, as a Potent Inhibitor of ER stress-induced XBP1 mRNA Splicing　Ri M*, Tashiro E*, Oikawa D, Shinjo S, Tokuda M. Yokouchi Y, Narita T, Masaki A, Ito A, Ding J, Kusumoto S, Ishida T, Komatsu H, Shiotsu Y, Ueda R, Iwawaki T, Imoto M and Iida S　Blood Cancer J　2　e79　2012　
• [Original paper]　A chemical genetic study identifying diversity in cell migration signaling in cancer cells　Magi S, Tashiro E and Imoto M　Sci Rep　2　823　2012　
• [Original paper]　Synthesis and anti-migrative evaluation of moverastin derivatives　Sawada M, Kubo S, Matsumura K, Takemoto Y, Kobayashi H, Tashiro E, Kitahara T, Watanabe H and Imoto M　Bioorg Med Chem Lett　21　1385　2011　
• [Original paper]　A new, convenient cell-based screening method for small-molecule glycolytic inhibitors　Kitagawa M, Misawa M, Ogawa S, Tashiro E and Imoto M　Biosci Biotechnol Biochem　75　367　2011　
• [Original paper]　Quinotrierixin inhibited ER stress-induced XBP1 mRNA splicing through inhibition of protein synthesis　Yamamoto K, Tashiro E and Imoto M　Biosci Biotechnol Biochem　75　284　2011　
• [Original paper]　Mycotrienin II, a translation inhibitor that prevents ICAM-1 expression induced by pro-inflammatory cytokines　Yamada Y, Tashiro E, Taketani S, Imoto M and Kataoka T　J Antibiot (Tokoyo)　64　361　2011　
• [Original paper]　Generation of ‘Unnatural Natural Product’ library and identification of a small molecule inhibitor of XIAP　Kawamura T, Matsubara K, Otaka H, Tashiro E, Shindo K, Yanagita RC, Irie K and Imoto M　Bioorg Med Chem　19　4377　2011　
• [Original paper]　Involvement of 14-3-3 proteins in the second EGF-induced wave of Rac1 activation in the process of cell migration　Kobayashi H, Ogura Y, Sawada M, Nakayama R, Takano K, Minato Y, Takemoto Y, Tashiro E, Watanabe H and Imoto M　J Biol Chem　286　39259　2011　
• [Original paper]　Isolation and structure elucidation of a novel androgen antagonist, arabilin, produced by Streptomyces sp. MK756-CF1　Kawamura T, Fujimaki T, Hamanaka N, Torii K, Kobayashi H, Takahashi Y, Igarashi M, Kinoshita N, Nishimura Y, Tashiro E and Imoto M　J Antibiot (Tokoyo)　63　601　2010　
• [Original paper]　Metabolomic identification of the target of the filopodia protrusion inhibitor glucopiericidin A　Kitagawa M, Ikeda S, Tashiro E, Soga T and Imoto M　Chem Biol　17　989　2010　
• [Original paper]　Transcriptional regulation of human fibroblast growth factor receptor 1 by E2F-1　Kanai M, Tashiro E, Maruki H, Minato Y and Imoto M　Gene　438　49　2009　
• [Original paper]　V-ATPase Inhibitors Overcome Bcl-xL-mediated Chemoresistance through Restoration of a Caspase-independent Apoptotic Pathway　Sasazawa Y, Futamura Y, Tashiro E and Imoto M　Cancer Sci　100　1460　2009　
• [Original paper]　Oligomycin induced the proteasomal degradation of cyclin D1　Kanai M, Iba S, Okada R, Tashiro E and Imoto M　J Antibiot (Tokoyo)　62　425　2009　
• [Original paper]　Discovery of Incednine as a Potent Modulator of the Anti-apoptotic Function of Bcl-xL from Microbial Origin　Futamura Y, Sawa R, Umezawa Y, Igarashi M, Nakamura H, Hasegawa K, Yamasaki M, Tashiro E, Takahashi Y, Akamatsu Y and Imoto M　J Am Chem Soc　130　1822　2008　
• [Original paper]　Identification and characterization of mouse type II platelet-derived growth factor receptor a transcript　Minato Y*, Nihei Y*, Kodama Y, Tashiro E, Kanai M and Imoto M　Biosci Biotechnol Biochem　72　759　2008　
• [Original paper]　SAR study of a Novel Triene-ansamycin Group Compound, Quinotrierixin, and Related Compounds, as Inhibitors of ER Stress-induced XBP1 Activation. I. Taxonomy, Fermentation, Isolation, and Biological activities and SAR study　Kawamura T, Tashiro E, Yamamoto K, Shindo K and Imoto M　J Antibiot (Tokoyo)　61　303　2008　
• [Original paper]　SAR study of a Novel Triene-ansamycin Group Compound, Quinotrierixin, and Related Compounds, as Inhibitors of ER Stress-induced XBP1 Activation. II. Structure Elucidation　Kawamura T, Tashiro E, Shindo K and Imoto M　J Antibiot (Tokoyo)　61　312　2008　
• [Original paper]　Involvement of PP2A nuclear accumulation and subsequent inactivation of AP-1 in leptomycin B-inhibited cyclin D1 expression　Tsuchiya A, Tashiro E, Yoshida M and Imoto M　Oncogene　26　1522　2007　
• [Review]　Functions of cyclin D1 as an oncogene and regulation of cyclin D1 expression　Tashiro E, Tsuchiya A and Imoto M　Cancer Sci　98　629　2007　
• [Original paper]　Spliceostatin A targets SF3b and inhibits both splicing and nuclear retention of pre-mRNA　Kaida D, Motoyoshi H, Tashiro E, Nojima T, Hagiwara M, Ishigami K, Watanabe H, Kitahara T, Yoshida T, Nakajima H, Tani T, Horinouchi S and Yoshida M　Nat Chem Biol　3　576　2007　
• [Original paper]　Transcriptional regulation of a new transcript variant of human platelet-derived growth factor receptor α by E2F-1　Minato Y, Tashiro E, Kanai M, Nihei Y, Kodama Y and Imoto M　Gene　403　89　2007　
• [Original paper]　Trierixin, a Novel Inhibitor of ER Stress-induced XBP1 Activation from Streptomyces sp. I. Taxonomy, Fermentation, Isolation, and Biological activities　Tashiro E, Hironiwa N, Kitagawa M, Futamura Y, Suzuki S, Nishio M and Imoto M　J Antibiot (Tokoyo)　60　547　2007　
• [Original paper]　Trierixin, a Novel Inhibitor of ER Stress-induced XBP1 Activation from Streptomyces sp. II. Structure Elucidation　Futamura Y, Tashiro E, Hironiwa N, Kohno J, Nishio M, Shindo K and Imoto M　J Antibiot (Tokoyo)　60　582　2007　
• [Original paper]　Suppression of multidrug resistance by migrastatin　Takemoto Y, Tashiro E and Imoto M　J Antibiot (Tokoyo)　59　435　2006　
• [Original paper]　GSK-3beta directly phosphorylates and activates MARK2/PAR-1　Kosuga S*, Tashiro E*, Kajioka T, Ueki M, Shimizu Y and Imoto M　J Biol Chem　280　42715　2005　
• [Original paper]　Chemistry and biology of moverastins, inhibitors of cancer cell migration, produced by Aspergillus　Takemoto Y, Watanabe H, Uchida K, Matsumura K, Nakae K, Tashiro E, Shindo K, Kitahara T and Imoto M　Chem Biol　12　1337　2005　
• [Original paper]　Involvement of nuclear accumulation of heat shock protein 27 in leptomycin B-induced apoptosis in HeLa cells　Tsuchiya A, Tashiro E, Yoshida M and Imoto M　J Antibiot (Tokoyo)　58　810　2005　
• [Original paper]　Overexpression of cyclin D1 contributes to malignancy by up-regulation of FGF receptor 1 via the pRB/E2F pathway　Tashiro E, Maruki H, Minato Y, Doki Y, Weinstein IB and Imoto M　Cancer Res　63　424　2003　
• [Original paper]　Regulation of FGF receptor-2 expression by transcription factor E2F-1　Tashiro E, Minato Y, Maruki H, Asagiri M and Imoto M　Oncogene　22　5630　2003　
• [Original paper]　Herbimycin A induces G1 arrest through accumulation of p27Kip1 in cyclin D1-overexpressing fibroblasts　Endo N, Tashiro E, Umezawa K, Kawada M, Uehara Y, Doki Y, Wesinstein IB and Imoto M　Biochem Biophys Res Commun　267　54　2000　
• [Original paper]　Inhibition of cyclin D1 expression and induction of apoptosis by Inostamycin in small cell lung carcinoma cells　Imoto M, Tanabe K, Simizu S, Tashiro E, Takada M and Umezawa K　Jpn J Cancer Res　89　315　1998　
• [Original paper]　Caspase-3 activation is not responsible for Vinblastine-induced Bcl-2 phosphorylation and G2/M arrest in small cell lung carcinoma Ms-1 cells　Tashiro E, Simizu S, Takada M, Umezawa K and Imoto M　Jpn J Cancer Res　89　940　1998　
• [Original paper]　Potentiation of Paclitaxel cytotoxicity by Inostamycin in human small cell lung carcinoma, Ms-1 cells　Simizu S, Tanabe K, Tashiro E, Takada M, Umezawa K and Imoto M　Jpn J Cancer Res　89　970　1998　

• View all