種別 タイトル 著者 誌名 巻号 ページ 出版年 DOI URL
"[Original paper]" "Ktedonoketone and 2'-oxosattabacin, benzenoid metabolites from a thermophilic bacterium Thermosporothrix hazakensis in the phylum Chloroflexi" "Igarashi Y, Yamamoto K, Ueno C, Yamada N, Saito K, Takahashi K, Enomoto M, Kuwahara S, Oikawa T, Tashiro E, Imoto M, Xiaohnyao Y, Zhou T, Harunari E, Oku N." "J Antibiot (Tokoyo)" 72 653 2019 10.1038/s41429-019-0195-7
[Review] "Screening and identification of inhibitors of endoplasmic reticulum stress-induced activation of the IRE1α-XBP1 branch" "Tashiro E" "J Antibiot (Tokoyo)" 72 899 2019 10.1038/s41429-019-0219-3
"[Original paper]" "14-3-3εa directs the pulsatile transport of basal factors towards the apical domain for lumen growth in tubulogenesis" "Mizotani Y, Suzuki M, Hotta K, Watanabe H, Shiba K, Inaba K, Tashiro E, Oka K, Imoto M." PNAS 115 E8873 2018 10.1073/pnas.1808756115
"[Original paper]" "Metacycloprodigiosin induced cell death selectively in β-catenin-mutated tumor cells" "Ikeda H, Shikata Y, Watanapokasin R, Tashiro E, Imoto M" "J Antibiot (Tokoyo)" 70 109 2017 10.1038/ja.2016.75
"[Original paper]" "Protein kinase A inhibition facilitates the antitumor activity of xanthohumol, a valosin-containing protein inhibitor" "Shikata Y, Yoshimaru T, Komatsu M, Katoh H, Sato R, Kanagaki S, Okazaki Y, Toyokuni S, Tashiro E, Ishikawa S, Katagiri T, Imoto M" "Cancer Sci" 108 785 2017 10.1111/cas.13175
"[Original paper]" "Nonthmicin, a Polyether Polyketide Bearing a Halogen-Modified Tetronate with Neuroprotective and Antiinvasive Activity from Actinomadura sp." "Igarashi Y, Natsuoka N, In Y, Kataura T, Tashiro E, Saiki I, Sudoh Y, Duangmal K, Thamchaipenet A" "Org Lett" 19 1406 2017 10.1021/acs.orglett.7b00318
[Review] "Chemistry and biology of the compounds that modulate cell migration" "Tashiro E and Imoto M" "J Ind Microbiol Biotechnol" 43 213 2016 10.1007/s10295-015-1654-1
"[Original paper]" "Involvement of the MEK/ERK pathway in EGF-induced E-cadherin down-regulation" "Tashiro E, Henmi S, Odake H, Ino S, Imoto M" "Biochem Biophys Res Commun" 477 801 2016 10.1016/j.bbrc.2016.06.138
"[Original paper]" "SMK-17, a MEK1/2-specific inhibitor, selectively induces apoptosis in β-catenin-mutated tumors" "Kiga M, Nakayama A, Shikata Y, Sasazawa Y, Murakami R, Nakanishi T, Tashiro E, and Imoto M" "Sci Rep" 5 8155 2015 10.1038/srep08155
"[Original paper]" "Apoptosis induction associated with the ER stress response through up-regulation of JNK in HeLa cells by gambogic acid" "Krajamg A, Imoto M, Tashiro E, Fujimaki T, Shinjo S, and Watanapokasin R" "BMC Complement Altem Med" 15 26 2015 10.1186/s12906-015-0544-4
"[Original paper]" "Evaluation of drug toxicity profiles based on the phenotypes of ascidian Ciona intestinalis" "Mizotani Y, Itoh S, Hotta K, Tashiro E, Oka K, and Imoto M" "Biochem Biophys Res Commun" 463 656 2015 10.1016/j.bbrc.2015.05.119
[Review] "Chemical biology of compounds obtained from screening using disease models" "Tashiro E and Imoto M" "Arch Pharm Res" 38 1651 2015 10.1007/s12272-015-0633-4
"[Original paper]" "5-lipoxygenase and cysteinyl leukotriene receptor 1 regulate epidermal growth factor-induced cell migration through Tiam1 upregulation and Rac1 activation" "Magi S, Takemoto Y, Kobayashi H, Kasamatsu M, Akita T, Tanaka A, Takano K, Tashiro E, Igarashi Y, and Imoto M" "Cancer Sci" 105 290 2014 10.1111/cas.12340
"[Original paper]" "Chemical genomic-based pathway analyses for epidermal growth factor-mediated signaling in migrating cancer cells" "Magi S, Saeki Y, Kasamatsu M, Tashiro E, and Imoto M" "PLoS One" 9 e96776 2014 10.1371/journal.pone.0096776
"[Original paper]" "Identification of licopyranocoumarin and glycyrurol from herbal medicines as neuroprotective compounds for Parkinson’s disease" "Fujimaki T, Saiki S, Tashiro E, Yamada D, Kitagawa M, Hattori N, and Imoto M" "PLoS One" 9 e100395 2014 10.1371/journal.pone.0100395
"[Original paper]" "Xanthohumol suppresses oestrogen-signaling in breast cancer through the inhibition of BIG3-PHB2 interactions" "Yoshimaru T, Komatsu M, Tashiro E, Imoto M, Osada H, Miyoshi Y, Honda J, Sasa M, and Katagiri T" "Sci Rep" 4 7355 2014 10.1038/srep07355
"[Original paper]" "Boronic Acid Inhibitors of Acyl Protein Thioesterase 1 and 2" "Zimmermann TJ, Burger M, Tashiro E, Kondoh Y, Martinez NE, Gormer K, Rosin-Steiner S, Shimizu T, Ozaki S, Mikoshiba K, Watanabe N, Hall D, Vetter IR, Osada H, Hedberg C and Waldmann H" Chembiochem 14 115 2013 10.1002/cbic.201200571
"[Original paper]" "Novel derivatives of aclacinomycin A block cancer cell migration through inhibition of farnesyl transferase" "Magi S, Shitara T, Takemoto Y, Sawada M, Kitagawa M, Tashiro E, Takahashi Y and Imoto M" "J Antibiot (Tokoyo)" 66 165 2013 10.1038/ja.2012.108
"[Original paper]" "Comparative Analysis of the UPR-Target Genes Expression Patterns induced by UPR-Inducing Compounds" "Shinjo S, Mizotani Y, Tashiro E and Imoto M" "Biosci Biotechnol Biochem" 77 729 2013
"[Original paper]" "Establishment of a new detection system for the dimerization of IRE1α using a BiFC assay" "Shinjo S, Tashiro E and Imoto M" "Biosci Biotechnol Biochem" 77 1333 2013
"[Original paper]" "Antitumor effects of novel highly hydrophilic and non-ATP-competitive MEK1/2 inhibitor, SMK-17" "Kiga M, Tanzawa F, Iwasaki S, Inaba F, Fujiwara K, Iwadare H, Echigo T, Nakamura Y, Shibata T, Suzuki K, Yasumatsu I, Nakayama A, Sasazawa Y, Tashiro E, Imoto M and Kurakata S" "Anticancer Drugs" 23 119 2012 10.1097/CAD.0b013e32834c6a33
[Review] "Target identification of bioactive compounds" "Tashiro E and Imoto M" "Bioorg Med Chem" 20 1910 2012 10.1016/j.bmc.2011.10.081
"[Original paper]" "Napyradiomycin A1, an inhibitor of mitochondrial complex I and II" "Yamamoto K, Tashiro E, Motohashi K, Seto H and Imoto M" "J Antibiot (Tokoyo)" 65 211 2012 10.1038/ja.2011.138
"[Original paper]" "Xanthohumol impairs autophagosome maturation through direct inhibition of valosin-containing protein" "Sasazawa Y, Kanagaki S, Tashiro E, Nogawa T, Muroi M, Kondoh Y, Osada H and Imoto M" "ACS Chem Biol" 7 892 2012 10.1021/cb200492h
"[Original paper]" "Inostamycin enhanced TRAIL-induced apoptosis through DR5 up-regulation on the cell surface" "Yamamoto K, Makino M, Watanapokasin R, Tashiro E and Imoto M" "J Antibiot (Tokoyo)" 65 295 2012 10.1038/ja.2012.21
"[Original paper]" "Identification of Toyocamycin, an agent cytotoxic for multiple myeloma cells, as a Potent Inhibitor of ER stress-induced XBP1 mRNA Splicing" "Ri M*, Tashiro E*, Oikawa D, Shinjo S, Tokuda M. Yokouchi Y, Narita T, Masaki A, Ito A, Ding J, Kusumoto S, Ishida T, Komatsu H, Shiotsu Y, Ueda R, Iwawaki T, Imoto M and Iida S" "Blood Cancer J" 2 e79 2012 10.1038/bcj.2012.26
"[Original paper]" "A chemical genetic study identifying diversity in cell migration signaling in cancer cells" "Magi S, Tashiro E and Imoto M" "Sci Rep" 2 823 2012 10.1038/srep00823
"[Original paper]" "Synthesis and anti-migrative evaluation of moverastin derivatives" "Sawada M, Kubo S, Matsumura K, Takemoto Y, Kobayashi H, Tashiro E, Kitahara T, Watanabe H and Imoto M" "Bioorg Med Chem Lett" 21 1385 2011 10.1016/j.bmcl.2011.01.028
"[Original paper]" "A new, convenient cell-based screening method for small-molecule glycolytic inhibitors" "Kitagawa M, Misawa M, Ogawa S, Tashiro E and Imoto M" "Biosci Biotechnol Biochem" 75 367 2011
"[Original paper]" "Quinotrierixin inhibited ER stress-induced XBP1 mRNA splicing through inhibition of protein synthesis" "Yamamoto K, Tashiro E and Imoto M" "Biosci Biotechnol Biochem" 75 284 2011
"[Original paper]" "Mycotrienin II, a translation inhibitor that prevents ICAM-1 expression induced by pro-inflammatory cytokines" "Yamada Y, Tashiro E, Taketani S, Imoto M and Kataoka T" "J Antibiot (Tokoyo)" 64 361 2011 10.1038/ja.2011.23
"[Original paper]" "Generation of ‘Unnatural Natural Product’ library and identification of a small molecule inhibitor of XIAP" "Kawamura T, Matsubara K, Otaka H, Tashiro E, Shindo K, Yanagita RC, Irie K and Imoto M" "Bioorg Med Chem" 19 4377 2011 10.1016/j.bmc.2011.05.009
"[Original paper]" "Involvement of 14-3-3 proteins in the second EGF-induced wave of Rac1 activation in the process of cell migration" "Kobayashi H, Ogura Y, Sawada M, Nakayama R, Takano K, Minato Y, Takemoto Y, Tashiro E, Watanabe H and Imoto M" "J Biol Chem" 286 39259 2011 10.1074/jbc.M111.255489
"[Original paper]" "Isolation and structure elucidation of a novel androgen antagonist, arabilin, produced by Streptomyces sp. MK756-CF1" "Kawamura T, Fujimaki T, Hamanaka N, Torii K, Kobayashi H, Takahashi Y, Igarashi M, Kinoshita N, Nishimura Y, Tashiro E and Imoto M" "J Antibiot (Tokoyo)" 63 601 2010 10.1038/ja.2010.98
"[Original paper]" "Metabolomic identification of the target of the filopodia protrusion inhibitor glucopiericidin A" "Kitagawa M, Ikeda S, Tashiro E, Soga T and Imoto M" "Chem Biol" 17 989 2010 10.1016/j.chembiol.2010.06.017
"[Original paper]" "Transcriptional regulation of human fibroblast growth factor receptor 1 by E2F-1" "Kanai M, Tashiro E, Maruki H, Minato Y and Imoto M" Gene 438 49 2009 10.1016/j.gene.2009.03.004
"[Original paper]" "V-ATPase Inhibitors Overcome Bcl-xL-mediated Chemoresistance through Restoration of a Caspase-independent Apoptotic Pathway" "Sasazawa Y, Futamura Y, Tashiro E and Imoto M" "Cancer Sci" 100 1460 2009 10.1111/j.1349-7006.2009.01194.x
"[Original paper]" "Oligomycin induced the proteasomal degradation of cyclin D1" "Kanai M, Iba S, Okada R, Tashiro E and Imoto M" "J Antibiot (Tokoyo)" 62 425 2009 10.1038/ja.2009.47
"[Original paper]" "Discovery of Incednine as a Potent Modulator of the Anti-apoptotic Function of Bcl-xL from Microbial Origin" "Futamura Y, Sawa R, Umezawa Y, Igarashi M, Nakamura H, Hasegawa K, Yamasaki M, Tashiro E, Takahashi Y, Akamatsu Y and Imoto M" "J Am Chem Soc" 130 1822 2008 10.1021/ja710124p
"[Original paper]" "Identification and characterization of mouse type II platelet-derived growth factor receptor a transcript" "Minato Y*, Nihei Y*, Kodama Y, Tashiro E, Kanai M and Imoto M" "Biosci Biotechnol Biochem" 72 759 2008
"[Original paper]" "SAR study of a Novel Triene-ansamycin Group Compound, Quinotrierixin, and Related Compounds, as Inhibitors of ER Stress-induced XBP1 Activation. I. Taxonomy, Fermentation, Isolation, and Biological activities and SAR study" "Kawamura T, Tashiro E, Yamamoto K, Shindo K and Imoto M" "J Antibiot (Tokoyo)" 61 303 2008 10.1038/ja.2008.43
"[Original paper]" "SAR study of a Novel Triene-ansamycin Group Compound, Quinotrierixin, and Related Compounds, as Inhibitors of ER Stress-induced XBP1 Activation. II. Structure Elucidation" "Kawamura T, Tashiro E, Shindo K and Imoto M" "J Antibiot (Tokoyo)" 61 312 2008 10.1038/ja.2008.44
"[Original paper]" "Involvement of PP2A nuclear accumulation and subsequent inactivation of AP-1 in leptomycin B-inhibited cyclin D1 expression" "Tsuchiya A, Tashiro E, Yoshida M and Imoto M" Oncogene 26 1522 2007
[Review] "Functions of cyclin D1 as an oncogene and regulation of cyclin D1 expression" "Tashiro E, Tsuchiya A and Imoto M" "Cancer Sci" 98 629 2007
"[Original paper]" "Spliceostatin A targets SF3b and inhibits both splicing and nuclear retention of pre-mRNA" "Kaida D, Motoyoshi H, Tashiro E, Nojima T, Hagiwara M, Ishigami K, Watanabe H, Kitahara T, Yoshida T, Nakajima H, Tani T, Horinouchi S and Yoshida M" "Nat Chem Biol" 3 576 2007
"[Original paper]" "Transcriptional regulation of a new transcript variant of human platelet-derived growth factor receptor α by E2F-1" "Minato Y, Tashiro E, Kanai M, Nihei Y, Kodama Y and Imoto M" Gene 403 89 2007
"[Original paper]" "Trierixin, a Novel Inhibitor of ER Stress-induced XBP1 Activation from Streptomyces sp. I. Taxonomy, Fermentation, Isolation, and Biological activities" "Tashiro E, Hironiwa N, Kitagawa M, Futamura Y, Suzuki S, Nishio M and Imoto M" "J Antibiot (Tokoyo)" 60 547 2007
"[Original paper]" "Trierixin, a Novel Inhibitor of ER Stress-induced XBP1 Activation from Streptomyces sp. II. Structure Elucidation" "Futamura Y, Tashiro E, Hironiwa N, Kohno J, Nishio M, Shindo K and Imoto M" "J Antibiot (Tokoyo)" 60 582 2007
"[Original paper]" "Suppression of multidrug resistance by migrastatin" "Takemoto Y, Tashiro E and Imoto M" "J Antibiot (Tokoyo)" 59 435 2006
"[Original paper]" "GSK-3beta directly phosphorylates and activates MARK2/PAR-1" "Kosuga S*, Tashiro E*, Kajioka T, Ueki M, Shimizu Y and Imoto M" "J Biol Chem" 280 42715 2005
"[Original paper]" "Chemistry and biology of moverastins, inhibitors of cancer cell migration, produced by Aspergillus" "Takemoto Y, Watanabe H, Uchida K, Matsumura K, Nakae K, Tashiro E, Shindo K, Kitahara T and Imoto M" "Chem Biol" 12 1337 2005
"[Original paper]" "Involvement of nuclear accumulation of heat shock protein 27 in leptomycin B-induced apoptosis in HeLa cells" "Tsuchiya A, Tashiro E, Yoshida M and Imoto M" "J Antibiot (Tokoyo)" 58 810 2005
"[Original paper]" "Overexpression of cyclin D1 contributes to malignancy by up-regulation of FGF receptor 1 via the pRB/E2F pathway" "Tashiro E, Maruki H, Minato Y, Doki Y, Weinstein IB and Imoto M" "Cancer Res" 63 424 2003
"[Original paper]" "Regulation of FGF receptor-2 expression by transcription factor E2F-1" "Tashiro E, Minato Y, Maruki H, Asagiri M and Imoto M" Oncogene 22 5630 2003
"[Original paper]" "Herbimycin A induces G1 arrest through accumulation of p27Kip1 in cyclin D1-overexpressing fibroblasts" "Endo N, Tashiro E, Umezawa K, Kawada M, Uehara Y, Doki Y, Wesinstein IB and Imoto M" "Biochem Biophys Res Commun" 267 54 2000
"[Original paper]" "Inhibition of cyclin D1 expression and induction of apoptosis by Inostamycin in small cell lung carcinoma cells" "Imoto M, Tanabe K, Simizu S, Tashiro E, Takada M and Umezawa K" "Jpn J Cancer Res" 89 315 1998
"[Original paper]" "Caspase-3 activation is not responsible for Vinblastine-induced Bcl-2 phosphorylation and G2/M arrest in small cell lung carcinoma Ms-1 cells" "Tashiro E, Simizu S, Takada M, Umezawa K and Imoto M" "Jpn J Cancer Res" 89 940 1998
"[Original paper]" "Potentiation of Paclitaxel cytotoxicity by Inostamycin in human small cell lung carcinoma, Ms-1 cells" "Simizu S, Tanabe K, Tashiro E, Takada M, Umezawa K and Imoto M" "Jpn J Cancer Res" 89 970 1998