Profile

Name

Ryu Yamasaki

Affiliation

Laboratory of Pharmaceutical Organic Chemistry

Subjects

Fundamental Chemistry II
Fundamental Organic Chemistry II

Official title

Associate Professor

Degree

Ph. D

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Academic background

2004 Ph. D. Univ. of Tokyo (pharamaceutical Science)

Papers

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• Original paper　Structures and Reactivities of N-Alkenyl-Substituted Anilides: The “Magic” Methyl Effect on Alkene.　Ryu Yamasaki, Mariko Ono, Kento Morita, Ai Ito, Kazuo Fukuda, Iwao Okamoto　J. Org. Chem.　88 (20)　14487–14493　2023　
• Original paper　Synthesis and conformational analysis of N-aromatic acetamides bearing thiophene: effect of intramolecular chalcogen-chalcogen interaction on amide conformational stability. 　Ai Ito, Marino Asato, Yuki Asami, Kazuo Fukuda, Ryu Yamasaki, Iwao Okamoto　J. Org. Chem.　88 (11)　7075–7087　2023　
• Original paper　Structure and Additive-free Transamidation of Planar N-Cyano Amides.　Ryu Yamasaki, Yuko Okada, Hiromi Iizumi, Ai Ito, Kazuo Fukuda, Iwao Okamoto　J. Org. Chem.　88 (9)　5704–5712　2023　
• Original paper　Reversible on/off conformational switching of pentafluorobenzoyl amide triggered by acid vapor and sublimation　Ryu Yamasaki,* Misuzu Harada, Ai Ito, Kazuo Fukuda, Shota Masumoto, Satoru Karasawa and Iwao Okamoto　CrystEngComm　24(35)　6226-6231　2022　
• Original paper　Conformational Switch of Benzanilide Derivative Induced by Acid; Effect of Pentafluorobenzoyl Group　Ryu Yamasaki,* Misuzu Harada, Rino Nagata, Ai Ito, Kazuo Fukuda, and Iwao Okamoto　Journal of Organic Chemistry　87(13)　8469-9479　2022　
• Original paper　Hybrid molecule between platanic acid and LCL-161 as a yes-associated protein degrader　Naoko Nakano, Kazuo Fukuda, Estu Tashiro, Haruka Ishikawa, Waka Nagano, Rie Kawamoto, Alice Mori, Misao Watanabe, Ryu Yamasaki, Takahisa Nakane, Mikihiko Naito, Iwao Okamoto and Susumu Itoh　The Journal of Biochemistry　171(6)　631-640　2022　
• Original paper　Synthesis and crystal structures of N,N-diarylacetamides bearing two azulene rings　Ai Ito, Mayuko Watanabe, Ayako Ishii, Ryu Yamasaki, Iwao Okamoto　Tetrahedron Lett.　86　153523　2021　
• Original paper　Characterization of Push-Pull-Type Benzo[X]quinoline Derivatives (X = g or f): Environmentally Responsive Fluorescent Dyes with Multiple Functions　Yasufumi Fuchi, Tomohiro Umeno, Yuichiro Abe, Keita Ikeno, Ryu Yamasaki, Iwao Okamoto, Kazuteru Usui, and Satoru Karasawa　Journal of Organic Chemistry　85(20)　13177-13190　2020　
• [Original paper]　N-Ethynylation of Anilides Decreases Double-Bond Character of Amide Bond while Trans Conformation and Planarity　Ryu Yamasaki, Kento Morita, Hiromi Iizumi, Ai Ito, Kazuo Fukuda, and Iwao Okamoto　Chemistry- A European Journal　25(43)　10118–10122　2019　[Related links]
• [original paper]　Synthesis and Conformational analysis of N-aryl-N-(6-azulenyl)acetamides　Ai Ito, Ayako Ishii, Takamasa Amaki, Kazuo Fukuda, Ryu Yamasaki, Iwao Okamoto　Tetrahedron Lett.　60(19)　1929–1933　2019　
• [original paper]　Conformational analysis of N-aryl-N-(2-azulenyl)acetamides　Ai Ito, Takamasa Amaki, Ayako Ishii, Kazuo Fukuda, Ryu Yamasaki, Iwao Okamoto　Tetrahedron Lett.　59(45)　3994–3998　2018　
• [original paper]　Spontaneous and Direct Transformation of N,O-Diaryl Carbamates into Diarylureas　Ryu Yamasaki, Yutaka Honjo, Ai Ito, Kazuo Fukuda, and Iwao Okamoto　Chem. Pharm. Bull.　66(9)　880–884　2018　
• [Original paper]　Synthesis and conformational analysis of N-aryl-N-(3-thienyl)acetamides　Ai Ito, Yuki Asami, Marino Asato, Kazuo Fukuda, Ryu Yamasaki, Iwao Okamoto　Tetrahedron Lett.　59(25)　2454–2458　2018　
• [Original paper]　Acid-induced molecular-structural transformation of N-methyl aromatic oligoamides bearing pyridine-2-carboxamide　Ryu Yamasaki, Saori Fujikake, Ai Ito, Kentaro Migita, Nobuyoshi Morita, Osamu Tamura, and Iwao Okamoto　Tetrahedron Lett.　57(1)　56-59　2016　
• [Original paper]　Acid- and base-induced conformational alternations of N-aryl-N-troponyl amides　Ai Ito, Masanori Sato, Ryu Yamasaki, and Iwao Okamoto　 Tetrahedron Lett.　57(3)　438-441　2016　
• [Original paper]　Synthesis of [3]Rotaxanes that Utilize the Catalytic Activity of a Macrocyclic Phenanthroline-Cu Complex: Remarkable Effect of the Length of the Axe Precursor.　Yoshiaki Yamashita, Yuichiro Mutoh, Ryu Yamasaki, Takeshi Kasama, and Shinichi Saito　Chem. A Eur. J.　21(5)　2139-2145　2015　
• [Original paper]　A Macrocyclic Phenanthroline–Copper Complex with Less Steric Hindrance: Synthesis, Structure, and Application to the Synthesis of [2]Rotaxane.　Shinichi Saito, Takanori Ohkubo, Yukari Yamazaki, Tatsuyuki Yokoyama, Yuichiro Mutoh, Ryu Yamasaki, Takeshi Kasama　Bull. Chem. Soc. Jpn.　88(9)　1323-1330　2015　
• [Original paper]　Synthesis and Radical Polymerization of Methacrylate Endowed with Bicyclobis(g-butyrolactone) Moiety through Methylene Linker.　Ryu Yamasaki, Atsushi Sudo, Takeshi Endo　J. Poly. Sci. A.　53(21)　2462-2468　2015　
• [Original paper]　Synthesis of rotacatenanes by the combination of Cu-mediated threading reaction and the template method: the dual role of one ligand　Ryuto Hayashi, Kota Wakatsuki, Ryu Yamasaki, Yuichiro Mutoh, Takeshi Kasama, and Shinichi Saito　Chem. Commun.　50(2)　204-206　2014　
• [Original paper]　Acid-mediated Ring-Expansion Reaction of N-Aryl-2-vinylazetidines: Synthesis and Unanticipated Reactivity of Tetrahydrobenzazocines　Tomoaki Shimizu, Shunsuke Koya, Ryu Yamasaki, Yuichiro Mutoh, Isao Azumaya, and Shinichi Saito　J. Org. Chem.　79(10)　4367-4377　2014　
• [Original paper]　Ni-Catalyzed [4+3+2] Cycloaddition of Ethyl Cyclopropylideneacetate and Dienynes: Scope and Mechanistic Insights　Ryu Yamasaki, Masato Ohashi, Kyotaro Maeda, Takuya Kitamura, Minami Nakagawa, Korehito Kato, Tetsushi Fujita, Ryohei Kamura, Kazuto Kinoshita, Hyuma Masu, Isao Azumaya, Sensuke Ogoshi, Shinichi Saito　Chem. A Eur. J.　19(10)　3415-3425　2013　
• [Original paper]　Synthesis of Large [2]Rotaxanes. The Relationship between the Size of the Blocking Group and the Stability of the Rotaxane　Shinichi Saito, Eiko Takahashi, Kouta Wakatsuki, Kazuhiko Inoue, Tomoko Orikasa, Kenta Sakai, Ryu Yamasaki, Yuichiro Mutoh, and Takeshi Kasama　J. Org. Chem.　78(8)　3553-3560　2013　
• [Original paper]　Synthesis of monocyclic nine-membered compounds by the [4+3+2] cycloaddition-bond cleavage strategy　Ryu Yamasaki, Korehito Kato, Daichi Hanitani, Yuichiro Mutoh, Shinichi Saito　Tetrahedron Lett.　54(27)　3507-3509　2013　
• [Original paper]　Synthesis of [2]Rotaxanes by the Copper-Mediated Threading Reactions of Aryl Iodides with Alkynes　Kenta Ugajin, Eiko Takahashi, Ryu Yamasaki, Yuichiro Mutoh, Takeshi Kasama, and Shinichi Saito;　Org. Lett.　15(11)　2684-2687　2013　
• [Original paper]　Synthesis and Polymerization of Styrene Monomer Carrying Isothiocyanate Moiety and Its Copolymerization with HEMA Based on Chemo-Selectivity to Nucleophiles　Ryu Yamasaki and Takeshi Endo　J. Poly. Sci. A.　51(24)　5215-5220　2013　
• [Original paper]　Synthesis and structure of bidentate NHC-metal complexes with xanthene skelton; the formation of cis and trans complexes　Shinichi Saito, Takaya Kobayashi, Takeshi Makino, Hiromitsu Yamaguchi, Hiroki Muto, Isao Azumaya, Kosuke Katagiri, Ryu Yamasaki　Tetrahedron　68(43)　8931-8936　2012　
• [Original paper]　Cycloaddition Reaction of 2-Vinylaziridines with Benzyne: A Facile Access to 1-Benzazocine Derivatives　Takashi Aoki, Shunsuke Koya, Ryu Yamasaki, and Shinichi Saito　Org. Lett.　14(17)　4506-4509　2012　
• [Original paper]　Synthesis and properties of phenylogous amides　Ryu Yamasaki, Hirokazu Ikeda, Hyuma Masu, Isao Azumaya, Shinichi Saito　Tetrahedron　68(40)　8450-8456　2012　
• [Original paper]　[5+2] Cycloaddition Reaction of 2-Vinylaziridines and Sulfonyl Isocyanates. Synthesis of Seven-Membered Cyclic Ureas　Eri Kanno, Kenichi Yamanoi, Shunsuke Koya, Isao Azumaya, Hyuma Masu, Ryu Yamasaki, and Shinichi Saito　J. Org. Chem.　77(5)　2142-2148　2012　

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Conference, etc.

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• [Poster presentation]　フェニル-パーフルオロフェニル相互作用を利用したウレア、アミド化合物の構造解析　飯田 愛菜, 永田 理乃, 山﨑 龍, 伊藤 愛, 枡 飛雄真, 棚谷 綾, 影近 弘之, 岡本 巌　日本薬学会第１３６年会　横浜　2016/03/26〜2016/03/29
• [Poster presentation]　ピリミジンを有するN-アルキルピリジン-2,6-ジカルボン酸アミドの不斉結晶化　濱松 朱音, 伊藤 愛, 佐久間 優子, 廣瀬 良嗣, 山﨑 龍, 桝 飛雄真, 東屋 功, 岡本 巌　日本薬学会第１３６年会　横浜　2016/03/26〜2016/03/29
• [Poster presentation]　Control of molecular arrangement mediated by the interaction between benzene-perflfluorobenzene　Yamasaki R, Iida M, Nagata R, Ito A, Tanatani A, Kagechika, H, Okamoto I.　2015 環太平洋国際化学会議　ホノルル　2015/12/15〜2015/12/20
• [Poster presentation]　水素結合とフェニルーパーフルオロフェニル相互作用を利用した分子配列ー配向制御　山﨑　龍、飯田　愛菜、永田　理乃、伊藤　愛、桝　飛雄真、棚谷　綾、影近　弘之、岡本　巌　第41回反応と合成の進歩シンポ　吹田　2015/10/26〜2015/10/27
• [Poster presentation]　酸化還元応答型N-メチル芳香族アミドの立体構造特性と配座変換　伊藤 愛, 山﨑 龍, 岡本 巌　日本薬学会関東支部会　町田　2015/10/04
• [Poster presentation]　大環状N-アルキルピリジルアミド三量体をホスト分子とした共結晶化　伊藤 愛､児玉 大樹､張谷 香奈恵､小島 絵美､山﨑 龍､桝 飛雄真､東屋 功､岡本 巌　第26回基礎有機化学討論会　松山　2015/09/24〜2015/09/26
• [Poster presentation]　Ｎ−アルキルニコチン酸アミドとm-ハロピリジンとのカップリング反応による３，５−置換型ピリジン含有アミドの合成と構造解析　志村　佳恵、張谷　香奈恵、伊藤　愛、山﨑　龍、岡本　巌　日本薬学会関東支部　船橋　2015/09/12
• [Poster presentation]　N-ピリジル型および N-トロポニル型芳香族アミドの立体構造特性と構造変換　佐藤 正規、伊藤 愛、藤野 大人、山﨑 龍、岡本 巌　　第４４回複素環化学討論会　札幌　2015/09/10〜2015/09/12
• [Poster presentation]　Acid- and base induced conformational alternation of N,N-diarylamides bearing tropolone　Ito A, Sato M, Yamasaki R, Okamoto I.　アメリカ化学会　ボストン　2015/08/16〜2015/08/20
• [Poster presentation]　pH Dependent molecular folding and unfolding of macrocyclic N-alkyl pyridinecarboxamides　Hariya K, Kojima E, Yoshioka R, Ito A, Yamasaki R, Okamoto I.　10th ISMSC 2015　ストラスブルグ　2015/06/28〜2015/07/2
• [Poster presentation]　5-トロポロンジアゾニウム塩の脱プロトン化平衡を利用した新規カルベン前駆体の合成と特性　伊藤 愛, 山﨑 龍, 岡本 巌　日本薬学会第１３５年会　神戸　2015/03/25〜2015/03/27
• [Poster presentation]　N-アリール-N-トロポニル型芳香族アミドの立体構造特性と酸塩基応答型の構造変換　佐藤 正規, 伊藤 愛, 山﨑 龍, 岡本 巌　日本薬学会第１３５年会　神戸　2015/03/25〜2015/03/27

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