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"Int J Mol Sci" 24(3) 2659 2023 10.3390/ijms24032659 "[Original paper]" "Opposing roles of sphingosine 1-phosphate receptors 1 and 2 in fat deposition and glucose tolerance in obese male mice" "Asano M, Kajita K, Fuwa M, Kajita T, Mori I, Akahoshi N, Ishii I, Morita H" Endocrinology 164 1-13 2023 10.1210/endocr/bqad019 [Review] "The perspective of PPAR dual/pan agonists as therapeutic drugs against NAFLD" "Akihiro Honda, Isao Ishii" YAKUGAKUZASSHI 142 1335–1343 2022 10.1248/yakushi.22-00159-1 https://www.jstage.jst.go.jp/article/yakushi/142/12/142_22-00159-1/_article/-char/en "[Original Paper]" "Hydrogen sulfide attenuates lymphedema via the induction of lymphangiogenesis through a PI3K/Akt-dependent mechanism" "Suzuki J, Shimizu Y, Hayashi T, Che Y, Pu Z, Tsuzuki K, Narita S, Shibata R, Ishii I, Calvert JW, Murohara T" "J Am Heart Assoc" 11 e026889 2022 10.1161/jaha.122.026889 "[Original Papaer]" "Functional and Structural Insights into Human PPARα/δ/γ Subtype Selectivity of Bezafibrate, Fenofibric Acid, and Pemafibrate." "Honda, A.; Kamata, S.; Akahane, M.; Machida, Y.; Uchii, K.; Shiiyama, Y.; Habu, Y.; Miyawaki, S.; Kaneko, C.; Oyama, T.; Ishii, I. " "Int J Mol Sci" 23 4726 2022 10.3390/ijms23094726 "[Original Papaer]" "The function of SARS-CoV-2 spike protein is impaired by disulfide-bond disruption with mutation at cysteine-488 and by thiol-reactive N-acetyl-cysteine and glutathione." "Murae, M., Shimizu, Y., Yamamoto, Y., Kobayashi, A., Houri, M., Inoue, T., Irie, T., Gemba, R., Kondo, Y., Nakano, Y., Miyazaki, S., Yamada, D., Saitoh, A., Ishii, I., Onodera, T., Takahashi, Y., Wakita, T., Fukasawa, M., Noguchi, K." "Biochem Biophys Res Commun" 597 30–36 2022 10.1016/j.bbrc.2022.01.106 "[Original Papaer]" "A high-methionine diet for one-week induces a high accumulation of methionine in the cerebrospinal fluid and confers bipolar disorder-like behavior in mice." "Ishii, I.; Kamata, S.; Ito, S.; Shimonaga, A.; Koizumi, M.; Tsushima, M.; Miura, A.; Nagata, T.; Tosaka, Y.; Ohtani, H.; Kamichatani, W.; Akahoshi, N." "Int. J. Mol. Sci." 23 928 2022 10.3390/ijms23020928 "[Original Paper]" "The gasotransmitter hydrogen sulfide (H2S) prevents pathologic calcification (PC) in cartilage" "Nasi S, Ehirchlou D, Bertran J, Castelbianco M, Mitchell J, Ishii I, So A, Busso N" Antioxidants 10 1433 2021 10.3390/antiox10091433 [Review] "PPARalpha–Ligand Binding Modes Revealed by X-ray Crystallography" "Kamata S, Ishii I" YAKUGAKUZASSHI 141 1267–1274 2021 10.1248/yakushi.21-00138 https://www.jstage.jst.go.jp/article/yakushi/141/11/141_21-00138/_article/-char/en [Review] "Role of hydrogen sulfide producing and metabolizing enzymes: Insights from human genetic diseases and their mouse models." 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