種別 タイトル 著者 誌名 巻号 ページ 出版年 DOI URL
原著論文 "Hybrid molecule between platanic acid and LCL-161 as a yes-associated protein (YAP) degrader." "Nakano N, Fukuda K, Tashiro E, Ishikawa H, Nagano W, Kawamoto R, Mori A, Watanabe M, Yamazaki R, Nakane T, Naito M, Okamoto I, Itoh S." "J. Biochem." 171 631-640 2022 10.1093/jb/mvac021
原著論文 "Environmental and soil characteristics in Ephedra havitats of Uzbekistan." "Minami M, Taichi F, Honda Y, Ueno K, Shinozaki J, Itoh S, Takano A, Berdiyar J, Ivanovich Mattsev I, Nakane T." "J. Nat. Med." 75 246-258 2021 10.1007/s11418-020-01460-3
原著論文 "Narciclasine is a novel YAP inhibitor that disturbs interaction between YAP and TEAD4." "Kawamoto R, nakano N, Ishikawa H, Tashiro E, Nagano W, Sano K, Irie M, Ikuta M, Kishi F, Nakane T, Naito M, Itoh S." "BBA Adv." 1 100008 2021 10.1016/j.bbadva.2021.100008
原著論文 "Involvement of miR-3180-3p and miR-4632-5p in palmitic acid-induced insulin resistance." "Tashiro E, Nagasawa Y, Itoh S, Imoto M." "Mol. Cell. Endocrinol." 534 111371 2021 10.1016/j.mce.2021.111371
原著論文 "Endothelial-specific depletion of TGF-β signaling affects lymphatic function." "Fukasawa K, Hanada K, Ichikawa K, Hirashima M, Takagi T, Itoh S, Watabe T, Itoh F." "Inflamm. Regeneration" 41 35 2021 10.1186/s41232-021-00185-4
原著論文 "Dissociation of the AhR/ARNT complex by TGF-β/Smad signaling represses CYP1A1 gene expression and inhibits benze[a]pyrene-mediated cytotoxicity." "Nakano N, Sakata N, Katsu Y, Nochise D, Sato E, Takahashi Y, Yamaguchi S, Haga Y, Ikeno S, Motizuki M, Sano K, Yamasaki K, Miyazawa K, Itoh S." "J. Biol Chem." 295 9033–9051 2020 10.1074/jbc.RA120.013596
原著論文 "Physical and chemical characteristics of soils in Ephedra gerardiana and E. pachyclada habitats of Kali Gandaki Valley in Central Nepal." "Minami M, Mori T, Honda Y, Ueno K, Murakami T, Ajioka Y, Atsumi T, Joshi KJ, Yadav PM, Kandel DR, Nakano M, Shinozaki J, Itoh S, Nakane T, Takano A. " " J. Nat. Med." 74 825-833 2020 10.1007/s11418-020-01413-w
原著論文 "Smad7 enhances TGF-β-induced transcription of c-Jun and HDAC6 promoting invasion of prostate cancer cells." "Thakur N, Hamidi A, Song J, Itoh S, Bergh A, Heldin CH, Landström M." iScience 23 101470 2020 10.1016/j.isci.2020.101470
原著論文 "PDZK1-interacting protein 1 (PDZK1IP1) traps Smad4 protein and suppresses transforming growth factor-β (TGF-β) signaling." "Ikeno S, Nakano N, Sano K, Minowa T, Sato W, Akatsu R, Sakata N, Hanagata N, Fujii M, Itoh F, Itoh S." "J. Biol Chem." 294 4966-4980 2019 10.1074/jbc.RA118.004153
総説 "TMEPAI family: involvement in regulation of multiple signaling pathways" "Itoh S, Ioth F." "Journal of Biochemistry" 164 195-204 2018 "doi: 10.1093/jb/mvy059" "https://doi.org/10.1093/jb/mvy059 "
原著論文 "TGF-β promotes PI3K-AKT signaling and prostate cancer cell migration through the TRAF6-mediated ubiquitylation of p85α." "Hamidi A, Song J, Itoh S, Marcusson A, Bergh ., Heldin C-H, Landström M" "Sci. Signal." 10 " eaal4186" 2017 10.1126/scisignal.aal4186
原著論文 "ネパール・Tistung Botanical Gardenでの薬用植物の試験栽培" "高野 昭人、中根 孝久、伊東 進、Kuber Jung Malla、Gopal Karki" 日本植物園協会誌 52 103-107 2017
総説 TGF-βシグナルを抑制するTMEPAIファミリー 伊東 進 生化学 89 145-153 2017 doi:10.14952/SEIKAGAKU.2017.890145 https://seikagaku.jbsoc.or.jp/10.14952/SEIKAGAKU.2017.890145/data/index.pdf
原著論文 "TMED10 interferes with TGF-β signaling by disrupting TGF-β receptor complex formation" "Nakano N, Tsuchiya Y, Kako K, Umezaki K, Sano K, Ikeno S, Otsuka E, Shigeta M, Nakagawa A, Sakata N, Itoh F, Nakano Y, Iemura S, van Dinther M, Natsume T, ten Dijke P, Itoh S" "J. Biol. Chem." 292 4099-4112 2017 "doi:10.1074/jbc.M116.769109 " http://www.jbc.org/content/292/10/4099.full.pdf?sid=a844e0f4-0c94-4aa7-b1fe-6a6ae6b136b5
原著論文 "Targeted degradation of proteins localized in subcellular compartments by hybrid small molecules" "Okuhira K, Shoda T, Omura R, Ohoka N, Hattori T, Shibata N, Demizu Y, Sugihara R, Ichino A, Kawahara H, Itoh Y, Ishikawa M, Hashimoto Y, Kurihara M, Itoh S, Saito H, Naito M." "Mol. Pharmacol." 91 159-166 2017 "https://doi.org/10.1124/mol.116.105569 " http://molpharm.aspetjournals.org/content/early/2016/12/12/mol.116.105569
原著論文 "Regulation of the TMEPAI promoter by TCF7L2: the C-terminal tail of TCF7L2 is essential to activate the TMEPAI gene." "Nakano N, Kato M, Itoh S" "J. Biochem." 159 27-30 2016 10.1093/jb/mvv117
原著論文 "Arf6 regulates tumor angiogenesis and growth through HGF-induced endothelial β1 integrin recycling. " "Hongu T, Funakoshi Y, Fukuhara S, Suzuki T, Sakimoto S, Takakura N, Ema M, Takahashi S, Itoh S, Kato M, Hasegawa H, Mochizuki N, Kanaho Y" "Nat. Commun." 6 7925 2015 10.1038/ncomms8925
原著論文 "TGF-β signaling enhancement by long-term exposure to hypoxia in a tumor microenvironment composed of Lewis lung carcinoma cells." "Furuta C, Miyamoto T, Takagi T, Noguchi Y, Kaneko J, Itoh S, Watanabe T, Itoh F" "Cancer Sci." 106 1524-1533 2015 10.1111/cas.12773
原著論文 "TGF-β signaling cooperates with AT motif-binding factor-1 for repression of the α-fetoprotein promoter." "Sakata N, Kaneko S, Ikeno S, Miura Y, Nakabayashi H, Dong X-Y, Dong J-T, Tamaoki T, Nakano N, Itoh S" "J. Signal Transduc." 2014 970346 2014 10.1155/2014/970346
原著論文 "C18 ORF1: a novel negative regulator of TGF-β signaling." "Nakano N, Maeyama K, Sakata N, Itoh F, Akatsu R, Nakata M, Katsu Y, Ikeno S, Vo Nguyen TT, Watanabe Y, Kato M, Itoh S" "J. Biol. Chem." 289 12680-12692 2014 10.1074/jbc.M114.558981
原著論文 "TMEPAI/PMEPA1enhances tumorigenic activities in lung cancer cells." "Vo Nguyen TT, Watanabe Y, Shiba A, Noguchi M, Itoh S, Kato M" "Cancer Sci." 105 334-341 2014 10.1111/cas.12355
総説 "Implication of TGF-β as a survival factor during tumour development." "Itoh S, Itoh F." "J. Biochem." 151 559-562 2012 10.1093/jb/mvs042
原著論文 "Delayed cutaneous wound healing in Fam129b/Minerva-deficient mice." "Oishi H, Itoh S, Matsumoto K, Ishitobi H, Suzuki R, Ema M, Kojima T, Uchida K, Kato M, Miyata T, Takahashi S" "J. Biochem." 152 549-555 2012 10.1093/jb/mvs100
原著論文 "Smad2/Smad3 in endothelium is indispensable for vascular stability via S1PR1 and N-cadherin expressions." "Itoh F., Itoh S., Adachi T., Ichikawa K., Matsumura Y., Takagi T., Festing M., Watanabe T., Weinstein M., Karlsson S., Kato M." Blood 119 5320-5328 2012 10.1182/blood-2011-12-395772
総説 "Inhibitory machinery for the TGF-β family signaling pathway." "Itoh S., Itoh F." "Growth Factors" 29 163-173 2011 10.3109/08977194.2011.614236
原著論文 "Interference of E2-2-mediated effect in endothelial cells by FAM96B through its limited expression of E2-2." "Yang W., Itoh F., Ohya H., Kishimoto F., Tanaka A., Nakano N., Itoh S., Kato M. " "Cancer Sci." 102 1808-1814 2011 10.1111/j.1349-7006.2011.02022.x
総説 TGF-βファミリーシグナル抑制機構 伊東 進 医学のあゆみ 234 893-899 2010
総説 概論―TGF-βファミリー研究の新しい流れ 宮澤 恵二、伊東 進 実験医学 28 850-855 2010
総説 血管新生におけるTGF-βファミリーの役割と疾患 伊東 史子、伊東 進、加藤 光保 実験医学 28 877-882 2010
原著論文 "Requirement of TCF7L2 for TGF-β-dependent transcriptional activation of the TMEPAI gene." "Nakano N, Itoh S, Watanabe Y, Maeyama K, Itoh F, Kato M." "J. Biol. Chem." 285 38023-38033 2010 10.1074/jbc.M110.132209
原著論文 "Flk1-GFP BAC Tg mice: an animal model for the study of blood vessel development. " "Ishitobi H., Matsumoto K., Azami T., Itoh F., Itoh S., Takahashi S., Ema M" "Exp. Animals" 59 615-622 2010 10.1538/expanim.59.615
原著論文 "Inhibition of endothelial cell activation by bHLH protein E2-2 and its impairment of angiogenesis." "Tanaka A., Itoh F., Nishiyama K., Takezawa T., Kurihara H., Itoh S., Kato M." Blood 115 4138-4147 2010 10.1182/blood-2009-05-223057
原著論文 "TMEPAI, a transmembrane TGF-β-inducible protein, sequesters from active participation in TGF-β signaling." "Watanabe Y., Itoh S., Goto T., Ohnishi, E., Inamitsu M., Itoh F., Satoh K., Wiercinska E., Yang W., Shi L., Tanaka A., Nakano N., Mommaas A. M., Shibuya H., ten Dijke P., Kato M." "Mol. Cell" 37 123-134 2010 10.1016/j.molcel.2009.10.028
原著論文 "Poor vessel formation in embryos from knock-in mice expressing ALK5 with L45 loop mutation defective in Smad activation." "Itoh F.#, Itoh S.#, Carvalho R. L. C.#, Adachi T., Ema M., Goumans M.-J., Larsson J., Karlsson S., Takahashi S., Mummery C. L., ten Dijke P., Kato M. (#equally contributed)" "Lab. Invest." 89 800-810 2009
原著論文 "TAL1/SCL relieves the E2-2-mediated repression of VEGFR2 promoter activity." "Tanaka A., Itoh F., Itoh S., Kato M." "J. Biochem." 145 129-135 2009
原著論文 "Ephrin-A1 promotes the malignant progression of intestinal tumors in Apcmin/+ mice." "Shi L., Itoh F., Itoh S., Takahashi S., Yamamoto M., Kato M" Oncogene 27 3265-3273 2008
総説 TGF-βファミリーシグナルとその調節機構 伊東 進、加藤 光保 細胞 39 322-326 2007
総説 "Negative regulation of TGF-β receptor/Smad signal transduction." "Itoh S., ten Dijke P." "Curr. Opinion Cell Biol." 19 176-184 2007
原著論文 "Compensatory mechanisms activated during vasculogenesis in mice by TGF-β-receptor deletion." "Carvalho R. L. C. #, Itoh F.#, Goumans M.-J., Lebrin F., Kato M., Takahashi S., Ema M., Itoh S., van Rooijen M., Bertolino P., ten Dijke P., Mummery C. L. (#equally contributed)" "J. Cell Sci" 120 4269-4277 2007
原著論文 "Methylation of Smad6 by protein arginine N-methyltransferase 1." "Inamitsu M., Itoh S., Hellman U., ten Dijke P., Kato M." "FEBS Lett." 580 6603-6611 2006
原著論文 "ELAC2, a putative prostate cancer susceptibility gene product, potentiates TGF-β/Smad-induced growth arrest of prostate cells." "Noda D.#, Itoh S.#, Watanabe Y., Inamitsu M., Dennler S., Itoh F., Koike S., Danielpour D., ten Dijke P., Kato M. (#equally contributed)" Oncogene 25 5591-5600 2006
原著論文 "Smad7 and protein phosphatase 1a are critical determinants in the duration of TGF-β/ALK1signaling in endothelial cells." "Valdimarsdóttir G., Goumans M.-J., Itoh F., Itoh S., Heldin C.-H., ten Dijke P" "BMC Cell. Biol." 0.3027777778 1-11 2006
原著論文 "Synergy and antagonism between Notch and BMP receptor signaling pathways in endothelial cells." "Itoh F.#, Itoh S.#, Goumans M.-J., Valdimarsdóttir G., Iso T., Dotto G. P., Hamamori Y., Kedes L., Kato M., ten Dijke P. (#equally contributed)" "EMBO J." 23 541-551 2004
原著論文 "Activin receptor-like kinase (ALK)1 is an antagonistic mediator of lateral TGFβ/ALK5 signaling." "Goumans M.-J., Valdimarsdóttir G., Itoh S., Lebrin F., Larsson J., Mummery C., Karlsson S., ten Dijke P." "Mol. Cell" 12 817-828 2003
原著論文 "Synthetic triterpenoids enhance TGF-β/Smad signaling." "Suh N., Roberts A. B., Birkey Reffey S., Miyazono K., Itoh S., ten Dijke P., Heiss E. H., Place A. E., Risingsong R., Wiliams C. R., Honda T., Gribble G. W., Sporn M. B." "Cancer Res." 63 1371-1376 2003
原著論文 "SARA and Hgs attenuate susceptibility to TGF-β1-mediated T cell suppression." "Kunzmann S., Wohlfahrt J. G., Itoh S., Asao H., Komada M., Akdis C. A., Blaser K., Schmidt-Weber C. B." "FASEB J." 17 194-202 2003
原著論文 "Elucidation of Smad requirement in transforming growth factor-β type I receptor-induced responses." "Itoh S., Thorikay M., Kowanetz M., Moustakas A., Itoh F., Heldin C.-H., ten Dijke P." "J. Biol. Chem." 278 3751-3761 2003
総説 "Regulation of cell proliferation by Smad proteins." "ten Dijke P., Goumans M.-J., Itoh F., Itoh S." "J. Cell. Physiol." 191 1-16 2002
原著論文 "Stimulation of Id1 expression by bone morphogenetic protein is sufficient and necessary for bone morphogenetic protein-induced activation of endothelial cells." "Valdimarsdóttir G., Goumans M.-J., Rosendahl A., Brugman M., Itoh S., Lebrin F., Sideras P., ten Dijke P." Circulation 106 2263-2270 2002
原著論文 "The FYVE domain in Smad anchor for receptor activation (SARA) is sufficient for localization of SARA in early endosomes and regulates TGF-β/Smad signaling." "Itoh F., Divecha N., Brocks L., Oomen L., Janssen H., Calafat J., Itoh S., ten Dijke P." "Gene Cells" 7 321-331 2002
原著論文 "Balancing the activation state of the endothelium via two distinct TGFβ type I receptors." "Goumans M.-J., Valdimarsdóttir G., Itoh S., Rosendahl A., Sideras P., ten Dijke P." "EMBO J" 21 1743-1753 2002
原著論文 "Promoting bone morphogenetic protein signaling through negative regulation of inhibitory Smads." "Itoh F., Asao H., Sugamura K., Heldin C.-H., ten Dijke P., Itoh S." "EMBO J" 20 4132-4142 2001
総説 "ラボレポート; アットホームなラボ：Dr. Peter ten-Dijke研究室" 伊東 進 実験医学 18 1545-1546 2000
総説 "Signaling of transforming growth factor-β family members through Smad proteins." "Itoh S., Itoh F., Goumans M.-J., ten Dijke P." "Eur. J. Biochem." 267 6954-6967 2000
総説 生体内活性型ビタミンD量を調節する酵素遺伝子の解析：くる病骨粗鬆症を予知する遺伝子診断法の確立への基礎的研究 伊東 進 薬学研究の進歩 16 1-5 2000
原著論文 "Functional consequences of tumorigenic missense mutations in the amino-terminal domain of Smad4." "Morén A., Itoh S., Moustakas A., ten Dijke P., Heldin C.-H." Oncogene 19 4396-4404 2000
原著論文 "The transcriptional co-activator p/CAF potentiates TGF-β/Smad signaling." "Itoh S., Ericsson J., Nishikawa J., Heldin C.-H. ten Dijke P." "Nucleic Acids Res." 28 4291-4298 2000
原著論文 "Smad7 mediates apoptosis induced by transforming growth factor-β in prostatic carcinoma cells. " "Landström M., Heldin N.-E., Bu S., Hermansson A., Itoh S., ten Dijke P., Heldin C.-H." "Curr. Biol." 10 535-538 2000
原著論文 "Molecular cloing and characterization of a novel human STE20-like kinase, hSLK(1)." "Yamada E., Tsujikawa K., Itoh S., Kameda Y., Kohama Y., Yamamoto H." "Biochim. Biophys. Acta" 1495 250-262 2000
原著論文 "Hedgehog creates a gradient of dpp activity in Drosophila wing imaginal discs." "Tanimoto H., Itoh S., ten Dijke P., Tabata T." "Mol. Cell" 5 59-71 2000
原著論文 "Smad and AML proteins synergistically confer transforming growth factor β1 responsiveness to human germ-line IgA genes." "Pardali E.#, Xie X.-Q.#, Tsapogas P., Itoh S., Arvanitidis K., Heldin C.-H., ten Dijke P., Grundström T., Sideras P. (#equally contributed)" "J. Biol. Chem." 275 3552-3560 2000
原著論文 "Xenopus Smad4β is the Co-Smad component of developmentally-regulated transcription factor complexes responsible forinduction of early mesodermal genes." "Howell M., Itoh F., Pierreux C. E., Valgeirsdóttir S., Itoh S., ten Dijke P., Hill C. S." "Dev. Biol." 214 354-369 1999
原著論文 "The L45 loop in type I receptors for TGF-β family members is a critical determinant in specifying Smad isoform activation." "Persson U.#, Izumi H.#, Souchelnytskyi S., Itoh S., Grimsby S., Engström U., Heldin C.-H., Funa K., ten Dijke P. (#equally contributed)" "FEBS Lett." 434 83-87 1998
原著論文 "Transforming growth factor-β1 induces nuclear export of inhibitory Smad7." "Itoh S.#, Landström M.#, Hermansson A., Itoh F., Heldin C.-H., Heldin N.-E., ten Dijke P. (#equally contributed)" "J. Biol. Chem." 273 29195-29201 1998
原著論文 "Induction of Smad6 and Smad7 mRNA by TGF-β family members and negative feedback function for Smad7 in TGF-β signaling." "Afrakhte M., Morén A., Jossan S., Itoh S., Sampath K., Westermark B., Heldin C.-H., Heldin N.-E., ten Dijke P." "Biochem. Biophys. Res. Commun." 249 505-511 1998
原著論文 "Intracellular signaling of osteogenic protein-1 through Smad5 activation." "Tamaki K., Souchelnyskyi S., Itoh S., Nakao A., Sampath K., Heldin C.-H., ten Dijke P." "J. Cell. Physiol." 177 355-363 1998
原著論文 "Identification and functional characterization of a Smad binding element (SBE) in the Jun B promoter that acts as a transforming growth factorβ, activin and bone morphogenetic protein-inducible enhancer." "Jonk L. J. C.#/, Itoh S.#, Heldin C.-H., ten Dijke P., Kruijer W. (#equally contributed)" "J. Biol. Chem." 273 " 21145-21152" 1998
原著論文 "Effect of 26,26,26,27,27,27-hexafluoro-1,25- dihydroxyvitamin D on the expression of vitamin D-responsive genes in vitamin D-deficient mice." "Yoshimura T., Itoh S., Tsujikawa K., Yamada E., Ishii T., Iemura O., Kameda Y., Mimura T., Kohama Y." Pharmacology 57 286-294 1998
原著論文 "Direct binding of Smad3 and Smad4 to critical TGFβ-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene." "Dennler S., Itoh S., Vivien D., ten Dijke P., Huet S., Gauthier J.-M." "EMBO J." 17 3091-3100 1998
原著論文 "Molecular cloning and regulation of a novel guinea pig P450 (CYP3A20) which differs from guinea pig CYP3A14 in only two amino acid residues." "Mori T., Itoh S., Kamataki T." "Biochem. Mol. Biol. Int." 44 1245-1253 1998
原著論文 "Expression and characterization of dog CYP2D15 using baculovirus expression system." "Tasaki T., Nakamura A., Itoh S., Ohashi K., Yamamoto Y., Masuda M., Iwata H., Kazusaka A., Kamataki T., Fujita S." "J. Biochem." 123 62-168 1998
総説 薬物の光学異性体の体内における相互変換のメカニズムに関する研究 鎌滝 哲也、横井 毅、伊東 進、佐久間 勉 臨床薬理の進歩’97 11-17 1997
原著論文 "Regulation of CYP1A and CYP3A mRNAs by ascorbic acid in guinea pigs." "Mori T., Itoh S., Ohgiya S., Ishizaki K., Kamataki T." "Arch. Biochem. Biophys." 348 268-277 1997
原著論文 "Upstream stimulatory factor 1 (USF1) suppresses induction of CYP1A1 mRNA by 3-methylcholanthrene (MC) in HepG2 cells." "Takahashi Y., Nakayama K., Itoh S., Kamataki T." "Biochem. Biophys. Res. Commun." 240 293-297 1997
原著論文 "Inhibition of the transcription of CYP1A1 gene by the upstream stimulatory factor 1 in rabbits. Competitive binding of USF1 with AhR/Arnt complex." "Takahashi Y., Nakayama K., Itoh S., Fujii-Kuriyama Y., Kamataki T." "J. Biol. Chem." 272 30025-30031 1997
原著論文 "Identification of Smad7, a TGF-β-inducible antagonist of TGF-β signaling." "Nakao A., Afrakhte M., Morén A., Nakayama T., Christian J. L., Heuchel R., Itoh S., Heldin N.-E., Heldin C.-H., ten Dijke P." Nature 389 631-635 1997
原著論文 "Determination of FAD-binding domain in flavin-containing monooxygenase1 (FMO1)." "Kubo A., Itoh S., Itoh K., Kamataki T." "Arch. Biochem. Biophys." 345 271-277 1997
原著論文 "Low activity of aldehyde dehydrogenase (ALDH) in liver of Suncus murinus: possible explanation for high sensitivity to alcohol." "Itoh S., Matsuyama T., Kamataki T." "J. Toxicol. Sci." 22 111-115 1997
原著論文 "Promoter region of the human eosinophil cationic protein gene." "Itoh S.#, Yamada E.#, Yoshimura T., Iemura O., Tsujikawa K., Mimura T., Kohama Y. (#equally contributed)" Immunogenetics 46 156-158 1997
原著論文 "Mouse cytochrome P450 (cyp3a11): predominant expression in liver and capacity to activate aflatoxin B1." "Yanagimoto T., Itoh S., Sawada M., Kamataki T." "Arch. Biochem. Biophys." 340 215-218 1997
原著論文 "Molecular cloning and characterization of a novel putative STE-like Kinase in guinea pigs." "Itoh S., Kameda Y., Yamada E., Tsujikawa K., Mimura T., Kohama Y." "Arch. Biochem. Biophys." 340 201-207 1997
原著論文 "Opposite effects of isoniazid and fasting on the expression of CYP2E1 protein and mRNA in house musk shrew (Suncus murinus)." "Nakura H., Itoh S., Kusano H., Ishizone H., Kamataki T." "Biochem. Mol. Biol. Int." 41 293-301 1997
原著論文 "Molecular cloning of mouse liver flavin containing monooxygenase (FMO1) cDNA and characterization of the expression product: metabolism of the neurotoxin, 1,2,3,4-tetrahydroisoqinoline (TIQ)." "Itoh K., Nakamura K., Kimura T., Itoh S., Kamataki T." "J. Toxicol. Sci." 22 47-58 1997
原著論文 "Isolation of a promoter region in mouse Cytochrome P450 3A (Cyp3A16) gene and its transcriptional control." "Itoh S., Abe Y., Kubo A., Okuda M., Shimoji M., Nakayama K., Kamataki T." "Biochim. Biophys. Acta" 1350 155-158 1997
原著論文 "Simultaneous expression of ferredoxin, ferredoxin reductase and P450 in COS7 cells." "Itoh S.#, Iemura O.#, Yoshimura T., Tsujikawa K., Yamada E., Nonaka Y., Okamoto M., Mimura T., Kohama Y. (#equally contributed)" "Biochim. Biophys. Acta" 1318 284-290 1997
原著論文 "Gene structure of mouse Cyp3a11: evidence for an enhancer element within its 5' flanking sequences." "Toide K., Itoh S., Nagasaka Y., Yanagimoto T., Kamataki T." "Arch. Biochem. Biophys." 338 43-49 1997
総説 好酸球分化・成熟に関連したシグナル分子 伊東 進、小濱 靖弘、三村 務 "Molecular Medicine" 33 594-601 1996
総説 カルシウムホメオスタシス：活性型ビタミンD3生合成・代謝酵素 伊東 進、小濱 靖弘、三村 務 "Molecular Medicine" 33 213-214 1996
原著論文 "Expression of aryl hydrocarbon receptor (AhR) and aryl hydrocarbon receptor nuclear translocator (Arnt) in adult rabbits known to be non-responsive to cytochrome P-450 1A1 (CYP1A1) inducers." "Takahashi Y., Nakayaka K., Shimojima T., Itoh S., Kamataki T." "Eur. J. Biochem." 242 512-518 1996
原著論文 "Application of primary hepatocytes from p53-knockout mice for studies of expression of Cyp3a." "Shimoji M., Itoh S., Toide K., Nakayama K., Aizawa S., Kamataki T." "J. Biochem." 120 42-48 1996
原著論文 "Increase of cytochrome b mRNA by bis(2-hydroxyethyl) trisulfide in J774A.1 cells." "Kohama Y., Iida K., Itoh S., Tsujikawa K., Mimura T." "Biol. Pharm. Bull." 19 876-878 1996
原著論文 "Expression of CYP3A7, a human fetus-specific cytochrome P450, in cultured cells and in the hepatocytes of p53-knockout mice." "Kamataki T., Hashimoto H., Shimoji M., Itoh S., Nakayama K., Hattori K., Yokoi T., Katsuki M., Aizawa S." "Toxicol. Lett." 82/83 879-882 1995
原著論文 "S-oxidation of (+)-cis-3,5-dimethyl-2-(3-pyridyl)- thiazolidin-4-one hydrochloride by rat hepatic flavin-containing monooxygenase 1 expressed in yeast." "Nunoya K., Yokoi T., Itoh K., Itoh S., Kimura K., Kamataki T." Xenobiotica 25 1283-1291 1995
原著論文 "Establishment of immortal hepatocytes from a CYP3A7-transgenic/p53- knockout mouse." "Shimoji M., Hattori K., Itoh S., Nakayama K., Katsuki M., Aizawa S., Yokoi T., Kamataki T." "Biochem. Biophys. Res. Commun." 21 1001-1005 1995
原著論文 "Tuna muscle peptide, PTHIKWGD, inhibits leukocyte-mediated injury and leukocyte adhesion to cultured endothelial cells." "Kohama Y., Kuroda T., Itoh S., Mimura T." "Biol. Pharm. Bull." 19 139-141 1995
原著論文 "cDNA cloning of mouse ferredoxin reductase from kidney." "Itoh S.#, Iemura O.#, Yamada E., Yoshimura T., Tsujikawa K., Kohama Y., Mimura T. (#equally contributed)" "Biochim. Biophys. Acta." 1264 159-162 1995
原著論文 "Molecular cloning of 25-hydroxyvitamin D3 24-hydroxylase (Cyp-24) from mouse kidney: its inducibility by vitamin D3." "Itoh S.#, Yoshimura T.#, Iemura O., Yamada E., Tsujikawa K., Kohama Y., Mimura T. (#equally contributed)" "Biochim. Biophys. Acta." 1264 26-28 1995
原著論文 "Pharmacological activity of chemically modified subfragment from human serum IgG. XIV. Effect of carboxamide-methylated light chain (G1L) on tyrosine phosphorylation and tumor necrosis factor-α (TNF-α) production from murine macrophages stimulated by lipopolysaccharide (LPS)." "Mimura T, Takeuchi K., Hiramatsu K., Tsujikawa K., Kohama Y., Itoh S." "Biol. Pharm. Bull." 18 1377-1381 1995
原著論文 "Mouse cytochrome P450 linked ferredoxin: its cDNA cloning and inducibility by dibutyryladenosine 3',5'-cyclic monophosphate and forskolin." "Itoh S.#, Iemura O#., Yamada E., Yoshimura T., Tsujikawa K, Kohama Y., Mimura T. (#equally contributed)" "Biochim. Biophys. Acta" 1263 173-175 1995
原著論文 "Simultaneous expression of human CYP3A7 and N-acetyltransferase in chinese hamster CHL cells results in high cytotoxicity for carcinogenic heterocyclic amines." "Hashimoto H., Yanagawa Y., Sawada M., Itoh S., Deguchi T., Kamataki T." "Arch. Biochem. Biophys." 320 323-329 1995
原著論文 "Evidence for lack of hepatic N- acetyltransferase in suncus (Suncus murinus)." "Nakura H., Itoh S., Kusano H., Ishizone H., Deguchi T., Kamataki T." "Biochem. Pharmacol." 50 1165-1170 1995
原著論文 "N-Oxygenation of 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine by the rat liver flavin-containing monooxygenase expressed in yeast cells." "Chiba K., Kobayashi K., Itoh K., Itoh S., Chiba T., Ishizaki T., Kamataki T." "Eur. J. Pharmacol." 293 " 97-100" 1995
原著論文 "Fetus-specific CYP3A7 and adult-specific CYP3A4 expressed in chinese hamster CHL cells have similar capacity to activate carcinogenic mycotoxins." "Hashimoto H., Nakagawa T., Yokoi T., Sawada M., Itoh S., Kamataki T." "Cancer Res." 55 787-791 1995
総説 ダイオキシンと結合する転写調節因子 伊東 進 ファルマシア 30 633-634 1994
原著論文 "A novel form of mouse cytochrome P450 3A (cyp3a-16): its cDNA cloning and expression in fetal liver." "Itoh S., Satoh M., Abe Y., Hashimoto H., Yanagimoto T., Kamataki T." "Eur. J. Biochem." 226 877-882 1994
原著論文 "Molecular cloning and functional expression of a mouse cytochrome P450 (cyp3a-13): examination of cyp3a-13 enzyme to activate aflatoxin B1 (AFB1)." "Yanagimoto T., Itoh S., Sawada M., Hashimoto H., Kamataki T." "Biochim. Biophys. Acta" 1201 405-410 1994
原著論文 "Studies on thermophile products. X. Further biological properties of isofatty acid-containing phosphatidylglycerol that enhances the induction of suppressor T cells." "Kohama Y., Semba T., Tanaka K., Iida K., Moriyama K., Suda T., Tone H., Itoh S., Mimura T." "Biol. Pharm. Bull." 17 1446-1450 1994
原著論文 "Characterization of the human Ah receptor promoter in human liver cell line, HepG2." "Takahashi Y., Itoh S., Shimojima T., Kamataki T." Pharmacogenetics 4 219-222 1994
原著論文 "Studies on thermophile products. IX. Isofatty acid-containing phosphatidylglycerol that enhances the induction of concanavalin A-activated suppressor T cells." "Kohama Y., Semba T., Tanaka K., Tone H., Tanaka S., Itoh S., Mimura T." "Biol. Pharm. Bull." 17 1171-1175 1994
原著論文 "Studies on thermophile products. VIII. Isolation of Bacillus stearothermophilus UBT8038, a Ccomponent that inhibits antigen presentation on mouse macrophages." "Kohama Y., Itoh M., Tanaka K., Semba T., Itoh S., Mimura T." "Biol. Pharm. Bull." 17 889-893 1994
原著論文 "Inhibitory effect of tuna peptide on endothelin production in cultured endothelial cells." "Kohama Y., Kuroda T., Iida K., Itoh S., Mimura T." "Biol. Pharm. Bull." 17 886-888 1994
原著論文 "Studies on thermophile products. VII. Effect of 1,3-di-methylpentadecanoyl glycerol and its related isofatty acids on T cell proliferation in vitro." "Kohama Y., Tanaka K., Takae S., Semba T., Tone H., Itoh S., Inada A., Nakanishi T., Mimura T." "Biol. Pharm. Bull." 17 850-852 1994
原著論文 "Stereoselective S-oxidation of flosequinan sulfide by rat hepatic flavin-containing monooxygenase 1A1 expressed in yeast." "Kashiyama E., Yokoi T., Itoh K., Itoh S., Odomi M., Kamataki T." "Biochem. Pharmacol." 47 1357-1363 1994
原著論文 "Structure and regulation of the human interferon regulatory factor 1 (IRF-1) and IRF-2 genes: implications for a gene network in the interferon system." "Harada H., Takahashi E., Itoh S., Harada K., Hori T., Taniguchi T." "Mol. Cell. Biol." 14 1500-1509 1994
原著論文 "Sex-related difference in the expression of cytochrome P450 in hamsters: cDNA cloning and examination for the expression of three distinct CYP2C cDNAs." "Sakuma T., Masaki K., Itoh S., Yokoi T., Kamataki T." "Mol. Pharmacol." 45 228-236 1994
原著論文 "Activities of drug-metabolizing enzymes in liver of Suncus murinus (suncus): possible lack of N-acetyltransferase activity in liver cytosol." "Nakura H., Itoh S., Kusano H., Ishizone H., Kamataki T." Pharmacology 48 201-204 1994
原著論文 "Gene structure of CYP3A4, an adult-specific form of cytochrome P450 in human livers and its transcriptional control." "Hashimoto H., Toide K., Kitamura R., Fujita M., Tagawa S., Itoh S., Kamataki T." "Eur. J. Biochem." 218 585-595 1993
原著論文 "High susceptibility to aflatoxin B1 and benzo(a)pyrene of BALB3T3 A31-1-1 cells expressing monkey CYP1A1." "Itoh S., Tagawa S., Sawada M., Kamataki T." "J. Toxicol. Sci." 18 207-210 1993
原著論文 "Human Ah receptor cDNA: analysis for highly conserved sequences." "Itoh S., Kamataki T." "Nucleic Acids Res." 21 3578 1993
原著論文 "Rat liver flavin-containing monooxygenase (FMO): cDNA cloning and expression in yeast." "Itoh K., Kimura T., Yokoi T., Itoh S., Kamataki T." "Biochim. Biophys. Acta" 1173 165-171 1993
原著論文 "Decrease in the content of cytochrome P-450IIE1 by fasting in liver microsomes of house musk shrew (Suncus murinus)." "Nakura H., Itoh S., Kusano H., Ishizone H., Imaoka S., Funae Y., Yokoi T., Kamataki T." "Biochem. Pharmacol." 43 1907-1910 1992
原著論文 "Mouse liver cytochrome P-450 (P-450IIIAM1): its cDNA cloning and inducibility by dexamethasone." "Yanagimoto T., Itoh S., Muller-Enoch D., Kamataki T." "Biochim. Biophys. Acta" 1130 329-332 1992
原著論文 "Genomic organization of human fetal specific P-450IIIA7 (cytochrome P-450HFLa)-related gene(s) and interaction of transcriptional regulatory factor with its DNA element in the 5' flanking region." "Itoh S., Yanagimoto T., Tagawa S., Hashimoto H., Kitamura R., Nakajima Y., Okochi T., Fujimoto S., Uchino J., Kamataki T." "Biochim. Biophys. Acta" 1130 133-138 1992
原著論文 "Stable expression of cytochrome P-450IIIA7 cDNA in human breast cancer cell line MCF-7 and application to cytotoxicity testing." "Kitamura R., Sato K., Sawada M., Itoh S., Kitada M., Komori M., Kamataki T." "Archs. Biochem. Biophys." 292 136-140 1992
原著論文 "Specific deletion of the B-cell population induced by aberrant expression of human interferon regulatory factor 1 gene in transgenic mice." "Yamada G., Ogawa M., Akagi K., Miyamoto H., Nakano N., Itoh S., Miyazaki J., Yamamura K., Taniguchi T." "Proc. Natl. Acad. Sci. USA" 88 532-536 1991
原著論文 "Assignment of human interferon regulatory factor-1 (IRF-1) gene to chromosome 5q23-q31." "Itoh S., Harada H., Nakamura Y., White R., Taniguchi T." Genomics 10 1097-1099 1991
原著論文 "Sequence of a cDNA coding for human IRF-2." "Itoh S., Harada H., Fujita T., Mimura T., Taniguchi T." "Nucleic Acids Res." 17 8372 1989
原著論文 "Transient induction of IL-2 receptor in cultured T cell lines by HTLV-1 LTR-linked Tax-1 gene." "Doi T., Hatakeyama M., Itoh S., Taniguchi T." "EMBO J." 8 1953-1958 1989
原著論文 "Ligand-dependent selection of the receptor gene: segregation of IL-2 binding activity and anti-Tac reactivity by a single amino acid alteration in the Tac antigen (p55)." "Minamoto S., Itoh S., Kono T., Doi T., Hatakeyama M." "Immunol. Lett." 20 139-148 1989
原著論文 "Studies on pharmacological activation of human serum immunoglobulin G (IgG) by chemical modification and active subfragments. VII. Effect of carboxamidemethylated Fc (CM-Fc) fragment from human serum IgG on lymphocyte and macrophages." "Mimura T., Itoh S., Tsujikawa K., Nakajima H., Kohama Y., Okabe M., Iwai M., Ohmura T., Yokoyama K." "Chem. Pharm. Bull." 35 4940-4945 1987
原著論文 "Studies on pharmacological activation of human serum immunoglobulin G (IgG) by chemical modification and active subfragments. VI. Anti-allergic activity of carboxamidemethylated Fc (CM-Fc) fragment from human serum IgG." "Mimura T., Itoh S., Tsujikawa K., Nakajima H., Kohama Y., Okabe M., Iwai M., Ohmura T., Yokoyama K." "Chem. Pharm. Bull." 35 4935-4939 1987
原著論文 "Inhibitory effect of bis[2-(E-2-alkenoylamino)ethyl] disulfides and 2-(E-octenoylamino)ethyl carbamoylmethyl sulfide on various inflammation models." "Mimura T., Nakajima H., Kohama Y., Okabe M., Tsujikawa K., Itoh S., Ohmura T., Iwai M., Yokoyama K." "Chem. Pharm. Bull." 35 4585-4591 1987
原著論文 "Inhibitory effect of bis[2-(E-2-alkenoylamino)ethyl] disulfides and 2-(E-octenoylamino)ethyl carbamoylmethyl sulfides on carrageenin-induced paw edema in rats." "Mimura T., Nakajima H., Kohama Y., Tsujikawa K., Itoh S., Ohmura T., Iwai M. Yokoyama K." "Chem. Pharm. Bull." 35 4579-4584 1987
原著論文 "Studies on biochemical activities of melanin from marine animals. V. Anti-inflammatory activity of low-molecular-weight melanoprotein from squid (Fr. SMII)." "Mimura T., Itoh S., Tsujikawa K., Nakajima H., Satake M., Kohama Y., Okabe M." "Chem. Pharm.Bull." 35 1144-1150 1987
原著論文 "Studies on pharmacological activation of human serum immunoglobulin g (IgG) by chemical modification and active subfragments. V. Mechanism of anti-inflammatory action of carboxamide-methylated l-chain (Fr. I-L) and H-chain Fr. I-H) from human serum IgG." "Mimura T., Tsujikawa K., Nakajima H., Itoh S., Okabe M., Kohda I., Yokoyama K." "J. Pharmacobio-Dyn." 9 799-805 1986